Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL835107 | 0.97 | KDR (0.76) | KDRPDGFRB | |
| SCHEMBL834139 | 0.92 | KDR (0.76) | KDRPDGFRB | |
| SCHEMBL835877 | 0.86 | KDR (0.72) | KDRPDGFRB | |
| SCHEMBL16782148 | 0.84 | KDR (1.00) | KDRPDGFRB | |
| SCHEMBL16782123 | 0.84 | KDR (1.00) | KDRPDGFRB | |
| SCHEMBL16782017 | 0.84 | KDR (1.00) | KDRPDGFRB | |
| SCHEMBL834823 | 0.84 | KDR (0.57) | KDRPDGFRB | |
| SCHEMBL11949578 | 0.84 | KDR (0.80) | KDRPDGFRB | |
| SCHEMBL17554532 | 0.83 | KDR (0.88) | KDRPDGFRB | |
| SCHEMBL16782065 | 0.83 | KDR (1.00) | KDRPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099757-A2 | SULFOXIMINES AS KINASE INHIBITORS | Allergan, Inc. (US) | 2009-09-16 | — | — | EP | disclosed |
| WO-2008061236-A2 | SULFOXIMINES AS KINASE INHIBITORS | ALLERGAN, INC. (US) | 2008-05-22 | — | — | WO | disclosed |