Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 18/20 | 0.57 |
| ▸ | GSK3B | P49841 | 1/20 | 0.54 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.48 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1553491 | 0.80 | PIK3C3 (0.51) | TGFBR1TGFBR2 | |
| SCHEMBL6127596 | 0.74 | NR3C2 (0.64) | NR3C2 | |
| SCHEMBL4543136 | 0.73 | NR3C2 (1.00) | NR3C2GSK3B | |
| SCHEMBL17939712 | 0.72 | PLCG1 (0.58) | — | |
| SCHEMBL17923108 | 0.72 | DYRK1A (0.50) | — | |
| SCHEMBL28673160 | 0.72 | CYP2A6 (0.49) | — | |
| SCHEMBL30879526 | 0.71 | CDK1 (0.62) | NR3C2GSK3B | |
| SCHEMBL25161315 | 0.70 | HDAC1 (0.51) | — | |
| SCHEMBL4542115 | 0.70 | NR3C2 (1.00) | NR3C2GSK3B | |
| SCHEMBL4540895 | 0.70 | NR3C2 (0.91) | NR3C2GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2102199-A1 | ANTIBACTERIAL POLYCYCLIC UREA COMPOUNDS | AstraZeneca AB (SE) | 2009-09-23 | — | — | EP | disclosed |
| WO-2008068470-A1 | ANTIBACTERIAL POLYCYCLIC UREA COMPOUNDS | ASTRAZENECA AB (SE) | 2008-06-12 | — | — | WO | disclosed |