Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 20/20 | 0.89 |
| ▸ | F3 | P13726 | 20/20 | 0.89 |
| ▸ | PLG | P00747 | 1/20 | 0.80 |
| ▸ | F2 | P00734 | 1/20 | 0.70 |
| ▸ | F10 | P00742 | 1/20 | 0.70 |
| ▸ | F11 | P03951 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2528445 | 1.00 | F7 (0.89) | F7F3PLGF2F10 | |
| SCHEMBL2528444 | 1.00 | F7 (0.89) | F7F3PLGF2F10 | |
| SCHEMBL2528779 | 0.94 | F7 (1.00) | F7F3PLG | |
| SCHEMBL2528781 | 0.94 | F7 (1.00) | F7F3PLG | |
| SCHEMBL3832858 | 0.94 | F7 (1.00) | F7F3PLG | |
| SCHEMBL12240962 | 0.89 | F7 (0.71) | F7F3PLGF2F10 | |
| SCHEMBL2528732 | 0.89 | F7 (1.00) | F7F3PLG | |
| SCHEMBL2528735 | 0.89 | F7 (1.00) | F7F3PLG | |
| SCHEMBL2528430 | 0.89 | F7 (1.00) | F7F3PLG | |
| SCHEMBL3908282 | 0.88 | F7 (1.00) | F7F3PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099783-A1 | BICYCLIC LACTAM FACTOR VIIA INHIBITORS USEFUL AS ANTICOAGULANTS | Brystol-Myers Squibb Company (US) | 2009-09-16 | — | — | EP | disclosed |
| WO-2008079759-A1 | BICYCLIC LACTAM FACTOR VIIA INHIBITORS USEFUL AS ANTICOAGULANTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2008-07-03 | — | — | WO | disclosed |