Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.48 |
| ▸ | ABHD6 | Q9BV23 | 4/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 10/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 8/20 | 0.37 |
| ▸ | XIAP | P98170 | 1/20 | 0.37 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 6/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3830648 | 0.83 | ESR1 (0.47) | ESR1ESR2ABHD6MTNR1BMTNR1A | |
| SCHEMBL1095205 | 0.82 | ESR1 (0.46) | ESR1ESR2ABHD6XIAPBIRC2 | |
| SCHEMBL3282323 | 0.79 | ESR1 (0.49) | ESR1ESR2 | |
| SCHEMBL1095555 | 0.79 | ESR1 (0.49) | ESR1ESR2 | |
| SCHEMBL3282297 | 0.79 | ESR1 (0.49) | ESR1ESR2 | |
| SCHEMBL31121204 | 0.79 | ESR1 (0.49) | ESR1ESR2 | |
| SCHEMBL1095106 | 0.77 | HTR2C (0.51) | ESR1ESR2ABHD6MTNR1B | |
| SCHEMBL1095168 | 0.77 | ESR1 (0.52) | ESR1ESR2ABHD6XIAPBIRC2 | |
| SCHEMBL4937667 | 0.77 | ESR1 (0.65) | ESR1ESR2ABHD6MTNR1B | |
| SCHEMBL1095538 | 0.77 | ESR1 (0.65) | ESR1ESR2ABHD6MTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1833473-B1 | 5HT2C RECEPTOR MODULATOR COMPOSITIONS AND METHODS OF USE | ARENA PHARM INC (US) | 2009-09-09 | — | — | EP | disclosed |