SCHEMBL383108

SCHEMBL383108

Brc1ccnc(Br)n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2174027 0.74
SCHEMBL21326988 0.72 CHRNA7 (0.35)
SCHEMBL14862098 0.72
SCHEMBL25468838 0.72
SCHEMBL14230908 0.72
SCHEMBL366280 0.72
SCHEMBL25401919 0.72
SCHEMBL18366964 0.72
SCHEMBL1198640 0.72
SCHEMBL8468185 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 253 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250361228-A1 PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF SOLUBLE GUANYLATE CYCLASE STIMULATORS CYCLERION THERAPEUTICS INC (US) 2025-11-27 US claimed
EP-4570797-A2 NOVEL PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF SOLUBLE GUANYLATE CYCLASE STIMULATORS Cyclerion Therapeutics, Inc. (US) 2025-06-18 EP claimed
US-12030874-B2 Processes and intermediates for the preparation of soluble guanylate cyclase stimulators CYCLERION THERAPEUTICS, INC. (US) 2024-07-09 US claimed
CN-118221665-A Methods and intermediates for preparing soluble guanylate cyclase stimulators 赛克里翁治疗有限公司 2024-06-21 CN claimed
CN-118184645-A Methods and intermediates for preparing soluble guanylate cyclase stimulators 赛克里翁治疗有限公司 2024-06-14 CN claimed
CN-111902410-B Methods and intermediates for preparing soluble guanylate cyclase stimulators 赛克里翁治疗有限公司 2024-04-19 CN claimed
US-20230339928-A1 NOVEL PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF SOLUBLE GUANYLATE CYCLASE STIMULATORS CYCLERION THERAPEUTICS, INC. 2023-10-26 US claimed
EP-4249469-A2 NOVEL PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF SOLUBLE GUANYLATE CYCLASE STIMULATORS Cyclerion Therapeutics, Inc. (US) 2023-09-27 EP claimed
EP-3737679-B1 NOVEL PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF SOLUBLE GUANYLATE CYCLASE STIMULATORS CYCLERION THERAPEUTICS INC (US) 2023-09-06 EP claimed
US-11708361-B2 Processes and intermediates for the preparation of soluble guanylate cyclase stimulators CYCLERION THERAPEUTICS, INC. (US) 2023-07-25 US claimed
US-11274096-B2 Processes and intermediates for the preparation of soluble guanylate cyclase stimulators CYCLERION THERAPEUTICS, INC. (US) 2022-03-15 US claimed
US-20220024909-A1 NOVEL PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF SOLUBLE GUANYLATE CYCLASE STIMULATORS CYCLERION THERAPEUTICS, INC. 2022-01-27 US claimed
US-20210053962-A1 NOVEL PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF SOLUBLE GUANYLATE CYCLASE STIMULATORS CYCLERION THERAPEUTICS, INC. 2021-02-25 US claimed
EP-3737679-A1 NOVEL PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF SOLUBLE GUANYLATE CYCLASE STIMULATORS Cyclerion Therapeutics, Inc. (US) 2020-11-18 EP claimed
CN-111902410-A Novel process and intermediates for the preparation of soluble guanylate cyclase stimulators 赛克里翁治疗有限公司 2020-11-06 CN claimed
WO-2019161534-A1 NOVEL PROCESSES AND INTERMEDIATES FOR PREPARATION OF SOLUBLE GUANYLATE CYCLASE STIMULATORS IRONWOOD PHARMACEUTICALS, INC. (US) 2019-08-29 WO claimed
CN-110106700-A A kind of cellulose base fiber fabric anti-pilling finishing liquid and method for sorting 苏州大学 2019-08-09 CN claimed
EP-0372623-A2 Flame-resistant polycarbonates containing units deriving from halogenated pyrimidine compounds in their polymer chain ENICHEM S.p.A. (IT) 1990-06-13 EP claimed
US-12624044-B2 SMARCA degraders and uses thereof KYMERA THERAPEUTICS, INC. (US) 2026-05-12 US disclosed
US-3988310-A FIBER-REACTIVE DYES; CELLULOSE BAYER AKTIENGESELLSCHAFT (DT) 1976-10-26 US disclosed