Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.53 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.53 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27593052 | 0.98 | HDAC3 (0.56) | TDP1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL27593059 | 0.98 | HDAC3 (0.56) | TDP1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL3833101 | 0.98 | HDAC3 (0.56) | TDP1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL3831105 | 0.95 | TDP1 (0.60) | TDP1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL3833098 | 0.93 | TDP1 (0.58) | TDP1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL27593058 | 0.93 | TDP1 (0.58) | TDP1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL27593049 | 0.93 | TDP1 (0.58) | TDP1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4570316 | 0.91 | TDP1 (0.60) | TDP1MAPK1SLC6A3HIF1ASLC6A2 | |
| SCHEMBL9065162 | 0.88 | TDP1 (0.62) | TDP1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL28875175 | 0.83 | TDP1 (0.68) | TDP1MAPK1SLC6A3HIF1ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1448508-B1 | DOUBLE ESTERS | DRUG DISCOVERY LAB AS (NO) | 2009-09-23 | — | — | EP | disclosed |
| CN-100516018-C | Double esters | PHOTOCURE ASA (NO) | 2009-07-22 | — | — | CN | disclosed |
| CN-1589254-A | Double esters | PHOTOCURE ASA (NO) | 2005-03-02 | — | — | CN | disclosed |
| EP-1448508-A1 | DOUBLE ESTERS | Photocure ASA (NO) | 2004-08-25 | — | — | EP | disclosed |
| WO-2003045893-A1 | DOUBLE ESTERS | PHOTOCURE ASA (NO) | 2003-06-05 | — | — | WO | disclosed |