Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.61 |
| ▸ | ERBB2 | P04626 | 20/20 | 0.61 |
| ▸ | ERBB4 | Q15303 | 5/20 | 0.57 |
| ▸ | ERBB3 | P21860 | 4/20 | 0.57 |
| ▸ | LCK | P06239 | 1/20 | 0.55 |
| ▸ | LYN | P07948 | 1/20 | 0.55 |
| ▸ | MET | P08581 | 1/20 | 0.55 |
| ▸ | SRC | P12931 | 1/20 | 0.55 |
| ▸ | CSK | P41240 | 1/20 | 0.55 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.55 |
| ▸ | TEK | Q02763 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3485029 | 0.99 | EGFR (0.60) | EGFRERBB2ERBB4ERBB3LCK | |
| SCHEMBL3483909 | 0.92 | EGFR (0.73) | EGFRERBB2ERBB4ERBB3 | |
| SCHEMBL3484147 | 0.88 | EGFR (0.63) | EGFRERBB2ERBB4ERBB3LCK | |
| SCHEMBL3484634 | 0.88 | EGFR (0.73) | EGFRERBB2ERBB4ERBB3LCK | |
| Hydrochloric Acid SCHEMBL3484497 | 0.87 | EGFR (0.60) | EGFRERBB2ERBB4ERBB3LCK | |
| SCHEMBL3484425 | 0.86 | EGFR (0.68) | EGFRERBB2ERBB4ERBB3LCK | |
| SCHEMBL3484696 | 0.85 | EGFR (0.74) | EGFRERBB2ERBB4ERBB3LCK | |
| SCHEMBL3484968 | 0.84 | EGFR (0.75) | EGFRERBB2ERBB4ERBB3LCK | |
| SCHEMBL3484603 | 0.84 | EGFR (0.69) | EGFRERBB2ERBB4ERBB3LCK | |
| SCHEMBL3832274 | 0.84 | EGFR (0.85) | EGFRERBB2ERBB4ERBB3LCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2103620-A1 | FUSED HETEROCYCLIC COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2009-09-23 | — | — | EP | disclosed |