⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17867065 | 0.78 | — | — | |
| SCHEMBL13944762 | 0.71 | — | — | |
| SCHEMBL3742393 | 0.69 | PIK3CG (0.59) | — | |
| SCHEMBL16431226 | 0.66 | — | — | |
| SCHEMBL24459 | 0.62 | — | — | |
| SCHEMBL4266121 | 0.60 | — | — | |
| SCHEMBL9386099 | 0.60 | — | — | |
| SCHEMBL1586293 | 0.60 | — | — | |
| Uric Acid SCHEMBL3325279 | 0.60 | — | — | |
| SCHEMBL4110072 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11708336-B2 | Anodic oxidation of 5-aminouracil | MEDIBEACON INC. (US) | 2023-07-25 | — | — | US | claimed |
| EP-4041235-A1 | ANODIC OXIDATION OF 5-AMINOURACIL | Medibeacon Inc. (US) | 2022-08-17 | — | — | EP | claimed |
| US-20220002254-A9 | ANODIC OXIDATION OF 5-AMINOURACIL | MEDIBEACON INC. | 2022-01-06 | — | — | US | claimed |
| US-20210107881-A1 | ANODIC OXIDATION OF 5-AMINOURACIL | MEDIBEACON INC (US) | 2021-04-15 | — | — | US | claimed |
| WO-2021072159-A1 | ANODIC OXIDATION OF 5-AMINOURACIL | MEDIBEACON INC. (US) | 2021-04-15 | — | — | WO | claimed |
| EP-2135863-A1 | Fluorescent pyrazine derivatives and methods of using the same in assessing renal function | Mallinckrodt, Inc. (US) | 2009-12-23 | — | — | EP | claimed |
| EP-1836175-A2 | FLUORESCENT PYRAZINE DERIVATIVES AND METHODS OF USING THE SAME IN ASSESSING RENAL FUNCTION | MALLINCKRODT, INC. (US) | 2007-09-26 | — | — | EP | claimed |
| WO-2006071759-A2 | FLUORESCENT PYRAZINE DERIVATIVES AND METHODS OF USING THE SAME IN ASSESSING RENAL FUNCTION | MALLINCKRODT INC. (US) | 2006-07-06 | — | — | WO | claimed |
| US-11708336-B2 | Anodic oxidation of 5-aminouracil | MEDIBEACON INC. (US) | 2023-07-25 | — | — | US | disclosed |
| US-11708336-B2 | Anodic oxidation of 5-aminouracil | MEDIBEACON INC. (US) | 2023-07-25 | — | — | US | disclosed |
| US-11708336-B2 | Anodic oxidation of 5-aminouracil | MEDIBEACON INC. (US) | 2023-07-25 | — | — | US | disclosed |
| US-11708336-B2 | Anodic oxidation of 5-aminouracil | MEDIBEACON INC. (US) | 2023-07-25 | — | — | US | disclosed |
| EP-4041235-A1 | ANODIC OXIDATION OF 5-AMINOURACIL | Medibeacon Inc. (US) | 2022-08-17 | — | — | EP | disclosed |
| EP-4041235-A1 | ANODIC OXIDATION OF 5-AMINOURACIL | Medibeacon Inc. (US) | 2022-08-17 | — | — | EP | disclosed |
| US-8778309-B2 | Fluorescent pyrazine derivatives and methods of using the same in assessing renal function | MEDIBEACON LLC (US) | 2014-07-15 | — | — | US | disclosed |
| US-8778309-B2 | Fluorescent pyrazine derivatives and methods of using the same in assessing renal function | MEDIBEACON LLC (US) | 2014-07-15 | — | — | US | disclosed |
| US-20140039191-A1 | Fluorescent Pyrazine Derivatives and Methods of Using the Same in Assessing Renal Function | Medibeacon, LLC (US) | 2014-02-06 | — | — | US | disclosed |
| EP-2039688-A1 | Fluorescent pyrazine derivatives and methods of using the same in assessing renal function | Mallinckrodt, Inc. (US) | 2009-03-25 | — | — | EP | disclosed |
| US-20090010851-A1 | Fluorescent Pyrazine Derivatives and Methods of Using the Same in Assessing Renal Function | MALLINCKRODT INC. (US) | 2009-01-08 | — | — | US | disclosed |
| EP-1854790-A1 | Fluorescent pyrazine derivatives and methods of using the same in assessing renal function | Mallinckrodt, Inc. (US) | 2007-11-14 | — | — | EP | disclosed |