Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 17/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 12/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.36 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3829607 | 0.96 | HDAC1 (0.38) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL4396605 | 0.93 | HDAC1 (0.37) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL3221345 | 0.91 | HDAC1 (0.37) | HDAC1HDAC6 | |
| SCHEMBL3835238 | 0.91 | HDAC1 (0.35) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL3226171 | 0.90 | HDAC1 (0.35) | HDAC1HDAC6 | |
| SCHEMBL3835556 | 0.90 | KDM1A (0.39) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL1496885 | 0.90 | HDAC1 (0.34) | HDAC1HDAC6HDAC3HDAC2NCOR2 | |
| SCHEMBL4398251 | 0.90 | KDM1A (0.38) | HDAC1HDAC6HDAC3HDAC2HDAC8 | |
| SCHEMBL3233994 | 0.90 | HDAC1 (0.35) | HDAC1HDAC6 | |
| SCHEMBL4392925 | 0.89 | TSHR (0.39) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2107052-A1 | NOVEL N-(2-AMINOPHENYL)BENZAMIDE DERIVATIVE HAVING AN UREA STRUCTURE | Santen Pharmaceutical Co., Ltd (JP) | 2009-10-07 | — | — | EP | disclosed |