Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3834555 | 1.00 | PIK3CA (0.67) | PIK3CAPIK3R1 | |
| Trifluoroacetic Acid SCHEMBL2377705 | 0.94 | PIK3CA (0.60) | PIK3CA | |
| SCHEMBL2377316 | 0.86 | PIK3CA (0.82) | PIK3CAPIK3R1 | |
| SCHEMBL2377709 | 0.86 | PIK3CA (0.51) | PIK3CA | |
| SCHEMBL2378420 | 0.85 | PIK3CA (0.69) | PIK3CAPIK3R1 | |
| SCHEMBL2375993 | 0.84 | PIK3CA (0.73) | PIK3CA | |
| SCHEMBL3831151 | 0.84 | PIK3CA (0.78) | PIK3CAPIK3R1 | |
| SCHEMBL12247634 | 0.83 | PIK3CA (0.69) | PIK3CA | |
| SCHEMBL2378966 | 0.83 | PIK3CA (0.71) | PIK3CA | |
| SCHEMBL12247649 | 0.83 | PIK3CA (0.78) | PIK3CAPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2050749-B1 | PYRIMIDINE DERIVATIVE AS PI3K INHIBITOR AND USE THEREOF | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2017-11-22 | — | — | EP | claimed |
| EP-2050749-A1 | PYRIMIDINE DERIVATIVE AS PI3K INHIBITOR AND USE THEREOF | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2009-04-22 | — | — | EP | claimed |