Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | PAM | P19021 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3831099 | 0.98 | TSHR (0.61) | TSHRMAPTRXFP1PAMHDAC3 | |
| SCHEMBL4389944 | 0.84 | TSHR (0.48) | TSHRMAPTRXFP1PAMHDAC3 | |
| SCHEMBL4388775 | 0.84 | TSHR (0.48) | TSHRMAPTRXFP1PAMHDAC3 | |
| SCHEMBL4389709 | 0.84 | TSHR (0.48) | TSHRMAPTRXFP1PAMHDAC3 | |
| SCHEMBL4389690 | 0.84 | TSHR (0.48) | TSHRMAPTRXFP1PAMHDAC3 | |
| SCHEMBL4381334 | 0.84 | TSHR (0.48) | TSHRMAPTRXFP1PAMHDAC3 | |
| SCHEMBL3830837 | 0.83 | HTT (0.47) | TSHRMAPTRXFP1HDAC3MAPK1 | |
| SCHEMBL4390818 | 0.82 | TSHR (0.49) | TSHRMAPTRXFP1PAMHDAC3 | |
| SCHEMBL4388755 | 0.80 | TSHR (0.50) | TSHRMAPTRXFP1PAMHDAC3 | |
| SCHEMBL4389706 | 0.79 | TSHR (0.51) | TSHRMAPTRXFP1PAMHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1448508-B1 | DOUBLE ESTERS | DRUG DISCOVERY LAB AS (NO) | 2009-09-23 | — | — | EP | disclosed |
| EP-1448508-A1 | DOUBLE ESTERS | Photocure ASA (NO) | 2004-08-25 | — | — | EP | disclosed |
| WO-2003045893-A1 | DOUBLE ESTERS | PHOTOCURE ASA (NO) | 2003-06-05 | — | — | WO | disclosed |