Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB1 | Q9H4B7 | 15/20 | 1.00 |
| ▸ | TUBB4A | P04350 | 14/20 | 1.00 |
| ▸ | TUBB | P07437 | 14/20 | 1.00 |
| ▸ | TUBA3C | P0DPH7 | 14/20 | 1.00 |
| ▸ | TUBA1B | P68363 | 14/20 | 1.00 |
| ▸ | TUBA4A | P68366 | 14/20 | 1.00 |
| ▸ | TUBB4B | P68371 | 14/20 | 1.00 |
| ▸ | TUBB3 | Q13509 | 14/20 | 1.00 |
| ▸ | TUBB2A | Q13885 | 14/20 | 1.00 |
| ▸ | TUBB8 | Q3ZCM7 | 14/20 | 1.00 |
| ▸ | TUBA3E | Q6PEY2 | 14/20 | 1.00 |
| ▸ | TUBA1A | Q71U36 | 14/20 | 1.00 |
| ▸ | TUBA1C | Q9BQE3 | 14/20 | 1.00 |
| ▸ | TUBB6 | Q9BUF5 | 14/20 | 1.00 |
| ▸ | TUBB2B | Q9BVA1 | 14/20 | 1.00 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.72 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.72 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.72 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.71 |
| ▸ | NQO2 | P16083 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1394056 | 1.00 | TUBB1 (1.00) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL1394054 | 1.00 | TUBB1 (1.00) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL2622579 | 0.93 | TUBB1 (0.86) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL6896671 | 0.92 | TUBB1 (0.85) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL631213 | 0.92 | TUBB1 (0.85) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL4659251 | 0.92 | TUBB1 (0.85) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| Phosphoric Acid SCHEMBL5071958 | 0.90 | TUBB1 (0.81) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| Sulfamate SCHEMBL21980870 | 0.89 | TUBB1 (0.79) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| Sulfamate SCHEMBL21980862 | 0.89 | TUBB1 (0.79) | TUBB1TUBB4ATUBBTUBA3CTUBA1B | |
| Sulfamate SCHEMBL21980873 | 0.89 | TUBB1 (0.79) | TUBB1TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9597299-B2 | Method for treating gefitinib-resistant non-small-cell lung cancer | MACAU UNIVERSITY OF SCIENCE AND TECHNOLOGY (MO) | 2017-03-21 | — | — | US | claimed |
| US-20160158163-A1 | Method For Treating Gefitinib-Resistant Non-Small-Cell Lung Cancer | MACAU UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2016-06-09 | — | — | US | claimed |
| US-5430062-A | Combretastatin analogues; inhibition of tubulin polymerization and colchicine binding; antitumor,-mitotic and -neoplastic agents | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1995-07-04 | — | — | US | claimed |
| US-9597299-B2 | Method for treating gefitinib-resistant non-small-cell lung cancer | MACAU UNIVERSITY OF SCIENCE AND TECHNOLOGY (MO) | 2017-03-21 | — | — | US | disclosed |
| US-9597299-B2 | Method for treating gefitinib-resistant non-small-cell lung cancer | MACAU UNIVERSITY OF SCIENCE AND TECHNOLOGY (MO) | 2017-03-21 | — | — | US | disclosed |
| US-20160158163-A1 | Method For Treating Gefitinib-Resistant Non-Small-Cell Lung Cancer | MACAU UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2016-06-09 | — | — | US | disclosed |
| US-20160158163-A1 | Method For Treating Gefitinib-Resistant Non-Small-Cell Lung Cancer | MACAU UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2016-06-09 | — | — | US | disclosed |
| EP-2065358-B1 | THE PREPARTION AND THE USE OF ETHOXY COMBRETASTATINS AND THEIR PRODRUGS | ZHEJIANG DADE PHARMACEUTICAL GROUP CO LTD (CN) | 2015-07-08 | — | — | EP | disclosed |
| EP-1248774-B1 | POLYHYDROXYSTILBENES AND STILBENE OXIDES AS ANTIPSORIATIC AGENTS AND PROTEIN KINASE INHIBITORS | WELICHEM BIOTECH INC (CA) | 2009-10-07 | — | — | EP | disclosed |
| US-6943194-B1 | Synthesis of phenstatin and prodrugs thereof | ARIZONA BOARD OF REGENTS, ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2005-09-13 | — | — | US | disclosed |
| US-6677383-B1 | SUPRRESION OF TUMORS CONTAINING OXIDOREDUCTASE ENZYMES, BY CONTACTING THE CELLS WITH ANTITUMOR CHEMICAL INTERMEDIATES SUCH AS 3,4,5-TRIMETHOXY-4'-METHOXYSTILBENE | DE MONTFORT UNIVERSITY (GB) | 2004-01-13 | — | — | US | disclosed |
| WO-1999034788-A1 | SYNTHESIS OF PHENSTATIN AND PRODRUGS THEREOF | ARIZONA BOARD OF REGENTS, A BODY CORPORATE, ACTING ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 1999-07-15 | — | — | WO | disclosed |
| EP-0754682-A1 | AMINOSTILBAZOLE DERIVATIVE AND MEDICINE | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1997-01-22 | — | — | EP | disclosed |
| US-5430062-A | Combretastatin analogues; inhibition of tubulin polymerization and colchicine binding; antitumor,-mitotic and -neoplastic agents | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1995-07-04 | — | — | US | disclosed |
| US-5430062-A | Combretastatin analogues; inhibition of tubulin polymerization and colchicine binding; antitumor,-mitotic and -neoplastic agents | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1995-07-04 | — | — | US | disclosed |
| EP-0641301-A1 | STILBENE DERIVATIVES AS ANTICANCER AGENTS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1995-03-08 | — | — | EP | disclosed |
| EP-0641301-A1 | STILBENE DERIVATIVES AS ANTICANCER AGENTS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1995-03-08 | — | — | EP | disclosed |
| WO-1993023357-B1 | STILBENE DERIVATIVES AS ANTICANCER AGENTS | — | 1994-01-06 | — | — | WO | disclosed |
| WO-1993023357-A1 | STILBENE DERIVATIVES AS ANTICANCER AGENTS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1993-11-25 | — | — | WO | disclosed |
| WO-1993023357-A1 | STILBENE DERIVATIVES AS ANTICANCER AGENTS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1993-11-25 | — | — | WO | disclosed |