⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3724778 | 0.74 | — | — | |
| SCHEMBL324327 | 0.74 | — | — | |
| SCHEMBL2076265 | 0.70 | — | — | |
| SCHEMBL791033 | 0.70 | — | — | |
| SCHEMBL1949175 | 0.70 | — | — | |
| SCHEMBL1465377 | 0.70 | — | — | |
| SCHEMBL13736145 | 0.70 | — | — | |
| SCHEMBL8631551 | 0.70 | — | — | |
| SCHEMBL1636152 | 0.70 | — | — | |
| SCHEMBL4986807 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3288940-A1 | AZABENZIMIDAZOLES AND THEIR USE AS AMPA RECEPTOR MODULATORS | Janssen Pharmaceutica NV (BE) | 2018-03-07 | — | — | EP | disclosed |
| WO-2016176460-A1 | AZABENZIMIDAZOLES AND THEIR USE AS AMPA RECEPTOR MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2016-11-03 | — | — | WO | disclosed |
| CN-101001846-B | Alkynyl derivatives as modulators of metabotropic glutamate receptors | ADDEX PHARMACEUTICALS SA | 2012-11-07 | — | — | CN | disclosed |
| CN-101454285-B | Oxadiazole derivatives as comt inhibitors | PORTELA & CA SA | 2012-06-27 | — | — | CN | disclosed |
| EP-1501361-B1 | 3-HETEROARYL SUBSTITUTED 5-METHYLOXYMETHYL ISOXAZOLINES USED AS HERBICIDES | BASF SE (DE) | 2009-09-30 | — | — | EP | disclosed |
| CN-101454285-A | Oxadiazole derivatives as comt inhibitors | PORTELA & CA SA (PT) | 2009-06-10 | — | — | CN | disclosed |
| US-7381687-B2 | 3-heteroaryl substituted 5-methyloxymethyl isoxazolines used as herbicides | BASF AKTIENGESELLSCHAFT (DE) | 2008-06-03 | — | — | US | disclosed |
| CN-101001846-A | Novel alkynyl derivatives as modulators of metabotropic glutamate receptors | ADDEX PHARMACEUTICALS SA (CH) | 2007-07-18 | — | — | CN | disclosed |
| US-20050165020-A1 | 3-heteroaryl substituted 5-methyloxymethyl isoxazolines used as herbicides | BASF AKTIENGESELLSCHAFT (DE) | 2005-07-28 | — | — | US | disclosed |