Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 19/20 | 0.50 |
| ▸ | CDK7 | P50613 | 4/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3835762 | 0.89 | CHEK1 (0.49) | CHEK1CDK7FFAR1 | |
| SCHEMBL3862660 | 0.88 | CHEK1 (0.55) | CHEK1CDK7 | |
| SCHEMBL3840941 | 0.84 | CHEK1 (0.50) | CHEK1CDK7 | |
| SCHEMBL3854180 | 0.83 | CHEK1 (0.70) | CHEK1CDK7 | |
| SCHEMBL5050598 | 0.82 | CHEK1 (0.53) | CHEK1CDK7 | |
| SCHEMBL5046867 | 0.74 | CHEK1 (0.53) | CHEK1CDK7 | |
| SCHEMBL3856005 | 0.74 | CHEK1 (0.58) | CHEK1CDK7 | |
| SCHEMBL5132488 | 0.74 | CHEK1 (0.56) | CHEK1CDK7 | |
| SCHEMBL5132049 | 0.74 | CHEK1 (0.59) | CHEK1CDK7 | |
| SCHEMBL5132784 | 0.74 | CHEK1 (0.68) | CHEK1CDK7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2108642-A1 | JAK INHIBITOR | Kyowa Hakko Kirin Co., Ltd. (JP) | 2009-10-14 | — | — | EP | disclosed |