Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ADH1B | P00325 | 1/20 | 0.30 |
| ▸ | ADH1C | P00326 | 1/20 | 0.30 |
| ▸ | ADH1A | P07327 | 1/20 | 0.30 |
| ▸ | ADH4 | P08319 | 1/20 | 0.30 |
| ▸ | ADH7 | P40394 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10881341 | 0.92 | EPHX1 (0.39) | EPHX1HPGDKMT2AADH1BADH1C | |
| SCHEMBL4652980 | 0.90 | EPHX1 (0.35) | EPHX1HPGDKMT2AADH1BADH1C | |
| SCHEMBL4654302 | 0.89 | — | — | |
| SCHEMBL11503387 | 0.87 | EPHX1 (0.39) | EPHX1HPGDKMT2AADH1BADH1C | |
| SCHEMBL5460780 | 0.87 | EPHX1 (0.39) | EPHX1HPGDKMT2AADH1BADH1C | |
| SCHEMBL1936361 | 0.87 | EPHX1 (0.39) | EPHX1HPGDKMT2AADH1BADH1C | |
| SCHEMBL5688 | 0.75 | — | — | |
| SCHEMBL1193091 | 0.72 | — | — | |
| SCHEMBL16530315 | 0.72 | EPHX1 (0.33) | EPHX1HPGDKMT2AADH1BADH1C | |
| SCHEMBL1396131 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1658267-B1 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2009-10-14 | — | — | EP | claimed |