Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 17/20 | 0.84 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.57 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.57 |
| ▸ | DUSP26 | Q9BV47 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3577388 | 0.91 | PIK3CG (1.00) | PIK3CG | |
| SCHEMBL2300757 | 0.84 | PIK3CG (0.72) | PIK3CG | |
| SCHEMBL3586596 | 0.83 | PIK3CG (1.00) | PIK3CGDUSP26 | |
| SCHEMBL21313685 | 0.82 | PIK3CG (0.87) | PIK3CG | |
| SCHEMBL3579454 | 0.81 | PIK3CG (1.00) | PIK3CG | |
| Potassium SCHEMBL3577211 | 0.80 | PIK3CG (0.98) | PIK3CG | |
| SCHEMBL3579243 | 0.79 | PIK3CG (1.00) | PIK3CG | |
| SCHEMBL3577703 | 0.78 | PIK3CG (1.00) | PIK3CG | |
| Potassium SCHEMBL3575892 | 0.78 | PIK3CG (0.98) | PIK3CG | |
| SCHEMBL21321260 | 0.77 | PIK3CG (0.78) | PIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2118076-B1 | QUINOXALINE COMPOUNDS AND USE THEREOF | MERCK SERONO SA (CH) | 2019-09-04 | — | — | EP | claimed |
| EP-2118076-A1 | QUINOXALINE COMPOUNDS AND USE THEREOF | Merck Serono S.A. (CH) | 2009-11-18 | — | — | EP | disclosed |
| WO-2008101979-A1 | QUINOXALINE COMPOUNDS AND USE THEREOF | MERCK SERONO S.A. (CH) | 2008-08-28 | — | — | WO | disclosed |