Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 20/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL502154 | 1.00 | NOTUM (0.41) | NOTUM | |
| SCHEMBL502155 | 1.00 | NOTUM (0.41) | NOTUM | |
| SCHEMBL3481434 | 1.00 | NOTUM (0.41) | NOTUM | |
| SCHEMBL501983 | 0.97 | NOTUM (0.42) | NOTUM | |
| SCHEMBL3482166 | 0.97 | NOTUM (0.42) | NOTUM | |
| SCHEMBL501984 | 0.97 | NOTUM (0.42) | NOTUM | |
| SCHEMBL501975 | 0.95 | NOTUM (0.39) | NOTUM | |
| SCHEMBL501974 | 0.95 | NOTUM (0.39) | NOTUM | |
| SCHEMBL3946497 | 0.95 | NOTUM (0.39) | NOTUM | |
| SCHEMBL15475242 | 0.94 | NOTUM (0.37) | NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7906652-B2 | Heterocycle-substituted 3-alkyl azetidine derivatives | MERCK SHARP & DOHME CORP. (US) | 2011-03-15 | — | — | US | disclosed |
| CN-101528730-A | Substituted imidazoles as bombesin receptor subtype-3 modulators | MERCK & CO INC (US) | 2009-09-09 | — | — | CN | disclosed |
| EP-2091937-A2 | SUBSTITUTED IMIDAZOLES AS BOMBESIN RECEPTOR SUBTYPE-3 MODULATORS | Merck & Co., Inc. (US) | 2009-08-26 | — | — | EP | disclosed |
| WO-2009042053-A2 | NEUROMEDIN U RECEPTOR AGONISTS AND USES THEREOF | MERCK & CO., INC. (US) | 2009-04-02 | — | — | WO | disclosed |
| WO-2008051406-A2 | SUBSTITUTED IMIDAZOLES AS BOMBESIN RECEPTOR SUBTYPE-3 MODULATORS | MERCK & CO., INC. (US) | 2008-05-02 | — | — | WO | disclosed |