Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT1A | P50416 | 18/20 | 0.70 |
| ▸ | CPT1B | Q92523 | 17/20 | 0.70 |
| ▸ | CPT2 | P23786 | 13/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3100704 | 0.94 | CPT1A (0.74) | CPT1ACPT1BCPT2ALDH1A1KMT2A | |
| SCHEMBL2900551 | 0.91 | CPT1A (0.76) | CPT1ACPT1BCPT2ALDH1A1KMT2A | |
| SCHEMBL3835852 | 0.89 | CPT1A (0.74) | CPT1ACPT1BCPT2ALDH1A1KMT2A | |
| SCHEMBL2907983 | 0.88 | CPT1A (0.74) | CPT1ACPT1BCPT2ALDH1A1KMT2A | |
| SCHEMBL3841723 | 0.87 | CPT1A (0.73) | CPT1ACPT1BCPT2ALDH1A1KMT2A | |
| SCHEMBL2904140 | 0.86 | CPT1A (0.76) | CPT1ACPT1BCPT2ALDH1A1KMT2A | |
| SCHEMBL3841719 | 0.85 | CPT1A (0.74) | CPT1ACPT1BCPT2ALDH1A1KMT2A | |
| SCHEMBL2898641 | 0.82 | CPT1A (1.00) | CPT1ACPT1BCPT2ALDH1A1 | |
| SCHEMBL2898003 | 0.82 | CPT1A (0.68) | CPT1ACPT1BCPT2ALDH1A1KMT2A | |
| SCHEMBL2903506 | 0.82 | CPT1A (0.84) | CPT1ACPT1BCPT2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2097373-A1 | SULFONAMIDE DERIVATIVES AS LIVER CARNITINE PALMITOYL TRANSFERASE (L-CPTL ) | F. Hoffmann-Roche AG (CH) | 2009-09-09 | — | — | EP | disclosed |
| WO-2008074692-A1 | SULFONAMIDE DERIVATIVES AS LIVER CARNITINE PALMITOYL TRANSFERASE (L-CPTL ) | F. HOFFMANN-LA ROCHE AG (CH) | 2008-06-26 | — | — | WO | disclosed |