Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 16/20 | 0.68 |
| ▸ | F9 | P00740 | 12/20 | 0.68 |
| ▸ | F2 | P00734 | 7/20 | 0.64 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.64 |
| ▸ | PRSS2 | P07478 | 7/20 | 0.64 |
| ▸ | PRSS3 | P35030 | 7/20 | 0.64 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3829912 | 0.81 | F10 (1.00) | F10F9F2PRSS1PRSS2 | |
| SCHEMBL3832713 | 0.81 | F10 (0.68) | F10F9F2PRSS1PRSS2 | |
| SCHEMBL3833446 | 0.79 | F10 (0.67) | F10F9F2PRSS1PRSS2 | |
| SCHEMBL6390603 | 0.79 | F10 (0.60) | F10F9F2PRSS1PRSS2 | |
| SCHEMBL3831605 | 0.78 | F10 (0.76) | F10F9F2PRSS1PRSS2 | |
| SCHEMBL7237224 | 0.78 | F10 (0.61) | F10F9F2PRSS1PRSS2 | |
| SCHEMBL17064344 | 0.76 | KLKB1 (0.84) | F10F9F2PRSS1PRSS2 | |
| SCHEMBL6391329 | 0.76 | F10 (0.61) | F10F9F2PRSS1PRSS2 | |
| SCHEMBL18605138 | 0.75 | KLKB1 (1.00) | F10F9F2PRSS1PRSS2 | |
| SCHEMBL3834842 | 0.75 | F10 (0.73) | F10F9F2PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946508-B1 | NITROGEN CONTAINING HETEROAROMATICS AS FACTOR Xa INHIBITORS | BRISTOL MYERS SQUIBB PHARMA CO (US) | 2009-09-23 | — | — | EP | claimed |