Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT1A | P50416 | 20/20 | 0.96 |
| ▸ | CPT1B | Q92523 | 20/20 | 0.96 |
| ▸ | CPT2 | P23786 | 10/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2904168 | 0.98 | CPT1A (1.00) | CPT1ACPT1BCPT2 | |
| SCHEMBL2900881 | 0.89 | CPT1A (0.84) | CPT1ACPT1BCPT2 | |
| SCHEMBL3836995 | 0.89 | CPT1A (0.84) | CPT1ACPT1BCPT2 | |
| SCHEMBL752613 | 0.85 | CPT1A (1.00) | CPT1ACPT1BCPT2 | |
| SCHEMBL752083 | 0.84 | CPT1A (1.00) | CPT1ACPT1BCPT2 | |
| SCHEMBL2897793 | 0.83 | CPT1A (0.82) | CPT1ACPT1BCPT2 | |
| SCHEMBL3580255 | 0.83 | CPT1A (1.00) | CPT1ACPT1BCPT2 | |
| SCHEMBL30014606 | 0.83 | CPT1A (1.00) | CPT1ACPT1BCPT2 | |
| SCHEMBL30015685 | 0.82 | CPT1A (0.91) | CPT1ACPT1BCPT2 | |
| SCHEMBL3569307 | 0.80 | CPT1A (0.88) | CPT1ACPT1BCPT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2097373-A1 | SULFONAMIDE DERIVATIVES AS LIVER CARNITINE PALMITOYL TRANSFERASE (L-CPTL ) | F. Hoffmann-Roche AG (CH) | 2009-09-09 | — | — | EP | disclosed |
| WO-2008074692-A1 | SULFONAMIDE DERIVATIVES AS LIVER CARNITINE PALMITOYL TRANSFERASE (L-CPTL ) | F. HOFFMANN-LA ROCHE AG (CH) | 2008-06-26 | — | — | WO | disclosed |