Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 6/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | TDO2 | P48775 | 1/20 | 0.31 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3835677 | 0.93 | NR1H2 (0.32) | NR1H2NR1H3 | |
| SCHEMBL3835072 | 0.87 | NR1H2 (0.34) | NR1H2IDO1TDO2IDO2NR1H3 | |
| SCHEMBL3039577 | 0.87 | NR1H2 (0.34) | NR1H2IDO1TDO2IDO2NR1H3 | |
| SCHEMBL3048091 | 0.86 | NR1H2 (0.33) | NR1H2IDO1TDO2IDO2NR1H3 | |
| SCHEMBL3034067 | 0.84 | NR1H2 (0.32) | NR1H2NR1H3 | |
| SCHEMBL3043957 | 0.83 | NR1H2 (0.33) | NR1H2IDO1TDO2IDO2NR1H3 | |
| SCHEMBL5049617 | 0.81 | POLB (0.34) | NR1H2 | |
| SCHEMBL3048293 | 0.81 | NR1H2 (0.33) | NR1H2IDO1TDO2IDO2NR1H3 | |
| SCHEMBL3044390 | 0.81 | POLB (0.39) | NR1H2 | |
| SCHEMBL3839027 | 0.81 | PARP1 (0.37) | NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2108642-A1 | JAK INHIBITOR | Kyowa Hakko Kirin Co., Ltd. (JP) | 2009-10-14 | — | — | EP | disclosed |