Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 17/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13818004 | 0.85 | MCHR1 (0.61) | MCHR1 | |
| SCHEMBL3837361 | 0.80 | MCHR1 (0.69) | MCHR1 | |
| SCHEMBL3832923 | 0.79 | MCHR1 (0.61) | MCHR1MAPT | |
| SCHEMBL3833412 | 0.79 | MCHR1 (0.65) | MCHR1 | |
| SCHEMBL3835524 | 0.78 | MCHR1 (0.64) | MCHR1 | |
| SCHEMBL3831980 | 0.76 | MCHR1 (0.67) | MCHR1SMN1; SMN2 | |
| SCHEMBL3831493 | 0.76 | MCHR1 (0.65) | MCHR1 | |
| SCHEMBL3832854 | 0.76 | MCHR1 (1.00) | MCHR1 | |
| SCHEMBL13817984 | 0.74 | MCHR1 (0.75) | MCHR1 | |
| SCHEMBL13817971 | 0.73 | MCHR1 (0.73) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1553089-B1 | ANTAGONIST OF MELANIN-CONCENTRATING HORMONE RECEPTOR COMPRISING BENZIMIDAZOLE DERIVATIVE AS ACTIVE INGREDIENT | BANYU PHARMA CO LTD (JP) | 2009-09-30 | — | — | EP | claimed |
| US-7541477-B2 | Antagonists to melanin-concentrating hormone receptor comprising benzimidazole derivative as active ingredient | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2009-06-02 | — | — | US | disclosed |
| US-7541477-B2 | Antagonists to melanin-concentrating hormone receptor comprising benzimidazole derivative as active ingredient | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2009-06-02 | — | — | US | disclosed |