⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL775960 | 0.64 | — | — | |
| 1,3-Dichloropropene SCHEMBL33877 | 0.64 | — | — | |
| Methylene Chloride SCHEMBL6677532 | 0.62 | — | — | |
| SCHEMBL5157362 | 0.62 | — | — | |
| SCHEMBL229347 | 0.62 | — | — | |
| SCHEMBL10400848 | 0.62 | — | — | |
| SCHEMBL258389 | 0.62 | — | — | |
| SCHEMBL234303 | 0.62 | — | — | |
| Methylene Chloride SCHEMBL6677529 | 0.62 | — | — | |
| SCHEMBL205123 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4595 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024104425-A1 | KRAS INHIBITOR COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | 广东东阳光药业股份有限公司 | 2024-05-23 | — | — | WO | claimed |
| CN-118047801-A | KRAS inhibitor compound, pharmaceutical composition and application thereof | 广东东阳光药业股份有限公司 | 2024-05-17 | — | — | CN | claimed |
| US-20240158417-A1 | SUBSTITUTED HETEROCYCLIC FUSED CYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | GENFLEET THERAPEUTICS (SHANGHAI) INC. (CN) | 2024-05-16 | — | — | US | claimed |
| WO-2024094163-A1 | POLYCYCLIC RING-FUSED DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | 上海翰森生物医药科技有限公司 | 2024-05-10 | — | — | WO | claimed |
| WO-2024078555-A1 | PYRIMIDOPYRIDINE COMPOUND, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | 广东东阳光药业股份有限公司 | 2024-04-18 | — | — | WO | claimed |
| CN-117886833-A | Pyrimidopyridine compound, pharmaceutical composition and application thereof | 广东东阳光药业股份有限公司 | 2024-04-16 | — | — | CN | claimed |
| WO-2024046454-A1 | HETEROARYL-SUBSTITUTED PYRIDOPYRROLIDONE DERIVATIVE, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | 上海海雁医药科技有限公司 | 2024-03-07 | — | — | WO | claimed |
| CN-117645614-A | Substituted heterocyclo-cyclic compounds, preparation and pharmaceutical use thereof | 劲方医药科技(上海)有限公司 | 2024-03-05 | — | — | CN | claimed |
| EP-4328229-A2 | SUBSTITUTED HETEROCYCLIC FUSED CYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | Genfleet Therapeutics (Shanghai) Inc. (CN) | 2024-02-28 | — | — | EP | claimed |
| WO-2023201780-A1 | METHOD FOR PREPARING QUINOLONE COMPOUND AND INTERMEDIATE THEREOF | 重庆文理学院 | 2023-10-26 | — | — | WO | claimed |
| EP-0148501-A1 | 5-Haloalkyl-1,3,4-thiadiazol-2-yloxyamides | BAYER AG (DE) | 1985-07-17 | — | — | EP | claimed |
| US-4514212-A | PRE-AND POSTEMERGENCE HERBICIDES | CIBA GEIGY CORPORATION (US) | 1985-04-30 | — | — | US | claimed |
| US-4486281-A | RELEASE COATINGS | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1984-12-04 | — | — | US | claimed |
| US-4412073-A | Isocyanurate preparation by catalytic, aminosilyl initiated cyclotrimerization of isocyanates | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1983-10-25 | — | — | US | claimed |
| US-4400379-A | ANTIBIOTICS | FUJISAWA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1983-08-23 | — | — | US | claimed |
| EP-0004747-B1 | PROCESSES FOR THE PREPARATION OF OLIGOMERIC PHOSPHATES ESTER COMPOSITIONS | STAUFFER CHEMICAL COMPANY (US) | 1982-06-02 | — | — | EP | claimed |
| EP-0015824-B1 | METAL DITHIOPHOSPHATES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS ADDITIVES FOR LUBRICATING OILS | OROGIL (FR) | 1982-02-17 | — | — | EP | claimed |
| US-4288384-A | N-Cyanoalkyl haloacetamides herbicidal antidotes | STAUFFER CHEMICAL COMPANY (US) | 1981-09-08 | — | — | US | claimed |
| US-4288335-A | REACTING ESTER WITH PHOSPHORUS SULFIDE, METAL OXIDE | OROGIL (FR) | 1981-09-08 | — | — | US | claimed |
| US-4089841-A | STABILIZERS/AGENTS | BAYER AG (DT) | 1978-05-16 | — | — | US | claimed |