Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.37 |
| ▸ | TACR1 | P25103 | 2/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3369193 | 0.90 | NR1H2 (0.46) | NR1H2NAMPTPDE4BTACR1RORC | |
| SCHEMBL3369192 | 0.90 | NR1H2 (0.46) | NR1H2NAMPTPDE4BTACR1RORC | |
| SCHEMBL1053828 | 0.90 | NR1H2 (0.46) | NR1H2NAMPTPDE4BTACR1RORC | |
| Water SCHEMBL1055202 | 0.89 | NR1H2 (0.44) | NR1H2NAMPTPDE4BTACR1RORC | |
| Water SCHEMBL1055969 | 0.89 | NR1H2 (0.44) | NR1H2NAMPTPDE4BTACR1RORC | |
| SCHEMBL2930654 | 0.84 | NR1H2 (0.50) | NR1H2NAMPTPDE4BMEN1ALDH1A1 | |
| SCHEMBL1052491 | 0.84 | NR1H2 (0.50) | NR1H2NAMPTPDE4BMEN1ALDH1A1 | |
| SCHEMBL2930651 | 0.84 | NR1H2 (0.50) | NR1H2NAMPTPDE4BMEN1ALDH1A1 | |
| SCHEMBL15684099 | 0.80 | NR1H2 (0.43) | NR1H2NAMPTPDE4BTACR1RORC | |
| SCHEMBL24555863 | 0.78 | NR1H2 (0.47) | NR1H2NAMPTPDE4BMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1473297-B1 | PROCESS FOR PRODUCING TERTIARY PHOSPHINE HAVING BULKY HYDROCARBON GROUP BONDED | HOKKO CHEM IND CO (JP) | 2009-10-14 | — | — | EP | claimed |
| US-7250535-B2 | Process for producing tertiary phosphine | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 2007-07-31 | — | — | US | claimed |
| US-20060020148-A1 | Process for producing tertiary phosphine having bulky hydrocarbon group bonded | HOLLO CHEMICAL INDUSTRY CO., LTD (JP) | 2006-01-26 | — | — | US | claimed |
| EP-1473297-A1 | PROCESS FOR PRODUCING TERTIARY PHOSPHINE HAVING BULKY HYDROCARBON GROUP BONDED | HOKKO CHEMICAL INDUSTRY CO. LTD. (JP) | 2004-11-03 | — | — | EP | claimed |
| EP-1473297-B1 | PROCESS FOR PRODUCING TERTIARY PHOSPHINE HAVING BULKY HYDROCARBON GROUP BONDED | HOKKO CHEM IND CO (JP) | 2009-10-14 | — | — | EP | disclosed |
| US-7250535-B2 | Process for producing tertiary phosphine | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 2007-07-31 | — | — | US | disclosed |
| US-20060020148-A1 | Process for producing tertiary phosphine having bulky hydrocarbon group bonded | HOLLO CHEMICAL INDUSTRY CO., LTD (JP) | 2006-01-26 | — | — | US | disclosed |
| EP-1473297-A1 | PROCESS FOR PRODUCING TERTIARY PHOSPHINE HAVING BULKY HYDROCARBON GROUP BONDED | HOKKO CHEMICAL INDUSTRY CO. LTD. (JP) | 2004-11-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060020148-A1 | Process for producing tertiary phosphine having bulky hydrocarbon group bonded | HRH3, HRH4, HRH1 | NR1H2 2040/4885NAMPT 4836/4885PDE4B 3295/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.