Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K9 | P80192 | 1/20 | 0.32 |
| ▸ | MAP3K11 | Q16584 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CLK1 | P49759 | 1/20 | 0.32 |
| ▸ | CLK2 | P49760 | 1/20 | 0.32 |
| ▸ | CLK3 | P49761 | 1/20 | 0.32 |
| ▸ | EED | O75530 | 1/20 | 0.31 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.31 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.31 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.31 |
| ▸ | NQO2 | P16083 | 1/20 | 0.31 |
| ▸ | EZH2 | Q15910 | 3/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3047855 | 0.84 | NQO2 (0.40) | KDM4EALDH1A1HPGDHSD17B10CLK1 | |
| SCHEMBL3839674 | 0.78 | PDE4B (0.33) | KDM4EALDH1A1HPGDHSD17B10CLK1 | |
| SCHEMBL3043948 | 0.76 | CLK1 (0.35) | MAP3K9MAP3K11CLK1CLK2CLK3 | |
| SCHEMBL3039550 | 0.76 | CLK1 (0.43) | MAP3K9MAP3K11CLK1CLK2CLK3 | |
| SCHEMBL3837330 | 0.74 | HSP90AB1 (0.33) | CLK1CLK2CLK3 | |
| Hydrochloric Acid SCHEMBL3037150 | 0.74 | PLK4 (0.35) | CLK2DPP4 | |
| SCHEMBL3039661 | 0.73 | CLK1 (0.35) | MAP3K9MAP3K11ALDH1A1HPGDTSHR | |
| SCHEMBL3837182 | 0.73 | CLK1 (0.35) | MAP3K9MAP3K11CLK1CLK2CLK3 | |
| SCHEMBL3037900 | 0.73 | PIK3CD (0.35) | MAP3K9MAP3K11CLK1CLK2CLK3 | |
| SCHEMBL15815035 | 0.73 | KDM4E (0.36) | KDM4EALDH1A1POLBHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2108642-A1 | JAK INHIBITOR | Kyowa Hakko Kirin Co., Ltd. (JP) | 2009-10-14 | — | — | EP | disclosed |