Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.59 |
| ▸ | TYMP | P19971 | 5/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | NT5E | P21589 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21905179 | 0.91 | TYMP (0.53) | ADORA2ATYMPADORA1ADORA3NT5E | |
| SCHEMBL16715145 | 0.84 | ADORA1 (0.75) | TYMPADORA1 | |
| SCHEMBL1068571 | 0.84 | ADORA1 (0.75) | TYMPADORA1 | |
| SCHEMBL15993919 | 0.84 | ADORA1 (0.75) | TYMPADORA1 | |
| SCHEMBL8359104 | 0.84 | ADORA1 (0.75) | TYMPADORA1 | |
| SCHEMBL1774838 | 0.83 | TYMP (0.63) | TYMPADORA1NT5E | |
| SCHEMBL1774839 | 0.83 | TYMP (0.63) | TYMPADORA1NT5E | |
| SCHEMBL29529385 | 0.83 | TYMP (0.63) | TYMPADORA1NT5E | |
| SCHEMBL29574745 | 0.83 | TYMP (0.63) | TYMPADORA1NT5E | |
| SCHEMBL7871248 | 0.83 | TYMP (0.63) | TYMPADORA1NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2408306-A1 | SUBSTITUTED NUCLEOSIDE AND NUCLEOTIDE ANALOGS | Alios Biopharma, Inc. (US) | 2012-01-25 | — | — | EP | disclosed |