Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 18/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5330620 | 0.85 | BRD4 (0.55) | BRD4CREBBPNR1H2CA12CA9 | |
| SCHEMBL3834970 | 0.84 | BRD4 (0.46) | BRD4CREBBPNR1H2CA12CA9 | |
| SCHEMBL3837235 | 0.83 | NR1H2 (0.35) | BRD4CREBBPNR1H2NR1H3 | |
| SCHEMBL3839418 | 0.80 | NR1H2 (0.35) | BRD4CREBBPNR1H2NR1H3 | |
| SCHEMBL3034386 | 0.77 | BRD4 (0.51) | BRD4CREBBPNR1H2CA12CA9 | |
| SCHEMBL5327142 | 0.77 | NR1H2 (0.51) | BRD4CREBBPNR1H2NR1H3 | |
| SCHEMBL18003246 | 0.76 | NR1H2 (0.59) | NR1H2CA12CA9NR1H3 | |
| SCHEMBL5327530 | 0.76 | AURKA (0.48) | BRD4CREBBPNR1H2CA12CA9 | |
| SCHEMBL3856349 | 0.75 | NR1H2 (0.35) | BRD4CREBBPNR1H2NR1H3 | |
| SCHEMBL3044207 | 0.75 | NR1H2 (0.38) | BRD4CREBBPNR1H2CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2108642-A1 | JAK INHIBITOR | Kyowa Hakko Kirin Co., Ltd. (JP) | 2009-10-14 | — | — | EP | disclosed |