Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 1/20 | 0.68 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.59 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.54 |
| ▸ | ANPEP | P15144 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15579942 | 1.00 | CSNK1E (0.68) | CSNK1EEPHX1SIGMAR1ANPEPSLC6A2 | |
| SCHEMBL11455433 | 0.98 | CSNK1E (0.71) | CSNK1EEPHX1SIGMAR1ANPEPSLC6A2 | |
| SCHEMBL8161936 | 0.98 | CSNK1E (0.71) | CSNK1EEPHX1SIGMAR1ANPEPSLC6A2 | |
| Hydrochloric Acid SCHEMBL29046415 | 0.98 | CSNK1E (0.66) | CSNK1EEPHX1SIGMAR1ANPEPSLC6A2 | |
| SCHEMBL10399079 | 0.98 | CSNK1E (0.71) | CSNK1EEPHX1SIGMAR1ANPEPSLC6A2 | |
| SCHEMBL873387 | 0.98 | CSNK1E (0.71) | CSNK1EEPHX1SIGMAR1ANPEPSLC6A2 | |
| SCHEMBL1829488 | 0.98 | CSNK1E (0.71) | CSNK1EEPHX1SIGMAR1ANPEPSLC6A2 | |
| SCHEMBL8420654 | 0.98 | CSNK1E (0.71) | CSNK1EEPHX1SIGMAR1ANPEPSLC6A2 | |
| SCHEMBL4878177 | 0.98 | CSNK1E (0.71) | CSNK1EEPHX1SIGMAR1ANPEPSLC6A2 | |
| Bromide SCHEMBL14128593 | 0.96 | CSNK1E (0.69) | CSNK1EEPHX1SIGMAR1ANPEPSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1477186-B1 | ANTIPRURITICS | SHIONOGI & CO (JP) | 2009-11-11 | — | — | EP | disclosed |
| EP-0572365-A2 | Heteroprostanoids, process for their production and therapeutical use thereof | NUOVO CONSORZIO SANITARIO NAZIONALE del Dott. Paolo Malizia & C. - S.A.S. (IT) | 1993-12-01 | — | — | EP | disclosed |