Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 16/20 | 0.47 |
| ▸ | PPARG | P37231 | 11/20 | 0.47 |
| ▸ | PPARD | Q03181 | 5/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.39 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3849871 | 0.99 | PPARA (0.48) | PPARAPPARGPPARDCYP4F2CYP4A11 | |
| SCHEMBL3845816 | 0.98 | PPARA (0.47) | PPARAPPARGPPARDCYP4F2CYP4A11 | |
| SCHEMBL3286740 | 0.96 | PPARA (0.54) | PPARAPPARGPPARDCYP4F2CYP4A11 | |
| SCHEMBL3841453 | 0.96 | PPARA (0.54) | PPARAPPARGPPARDCYP4F2CYP4A11 | |
| SCHEMBL3841355 | 0.95 | PPARA (0.47) | PPARAPPARGPPARDCYP4F2CYP4A11 | |
| SCHEMBL3287502 | 0.94 | PPARA (0.48) | PPARAPPARGPPARDCYP4F2CYP4A11 | |
| SCHEMBL3840924 | 0.93 | PPARA (0.43) | PPARAPPARGPPARDCYP4F2CYP4A11 | |
| SCHEMBL3842820 | 0.93 | PPARA (0.53) | PPARAPPARGPPARDCYP4F2CYP4A11 | |
| SCHEMBL3841935 | 0.93 | PPARA (0.48) | PPARAPPARGPPARDPCSK9 | |
| SCHEMBL3846682 | 0.93 | PPARA (0.48) | PPARAPPARGPPARDCYP4F2CYP4A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856065-B1 | 1,2,4-TRIAZINE DERIVATIVES, PREPARATION AND USE THEREOF IN HUMAN THERAPY | PF MEDICAMENT (FR) | 2009-11-11 | — | — | EP | claimed |
| EP-1856065-B1 | 1,2,4-TRIAZINE DERIVATIVES, PREPARATION AND USE THEREOF IN HUMAN THERAPY | PF MEDICAMENT (FR) | 2009-11-11 | — | — | EP | disclosed |