Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 9/20 | 0.48 |
| ▸ | PPARG | P37231 | 7/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | IDE | P14735 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3848274 | 0.98 | PPARA (0.47) | PPARAPPARGPPARDLMNAMAPT | |
| SCHEMBL3845333 | 0.95 | PPARA (0.46) | PPARAPPARGPPARDLMNAMAPT | |
| SCHEMBL3844352 | 0.93 | PPARA (0.48) | PPARAPPARGPPARDCNR1CNR2 | |
| SCHEMBL3842294 | 0.92 | PPARA (0.41) | PPARAPPARGPPARDLMNAMAPT | |
| SCHEMBL3848279 | 0.92 | PPARA (0.47) | PPARAPPARGPPARDCNR1CNR2 | |
| SCHEMBL3848017 | 0.91 | PPARA (0.61) | PPARAPPARGPPARDLMNAMAPT | |
| SCHEMBL3841464 | 0.91 | PPARA (0.48) | PPARAPPARGPPARDLMNAMAPT | |
| SCHEMBL3847164 | 0.90 | PPARA (0.40) | PPARAPPARGPPARDLMNAMAPT | |
| SCHEMBL3840689 | 0.89 | PPARA (0.47) | PPARAPPARGPPARDLMNAMAPT | |
| SCHEMBL3845277 | 0.89 | PPARA (0.45) | PPARAPPARGPPARDCNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856065-B1 | 1,2,4-TRIAZINE DERIVATIVES, PREPARATION AND USE THEREOF IN HUMAN THERAPY | PF MEDICAMENT (FR) | 2009-11-11 | — | — | EP | claimed |