Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 20/20 | 0.59 |
| ▸ | F2 | P00734 | 6/20 | 0.59 |
| ▸ | PLAT | P00750 | 1/20 | 0.44 |
| ▸ | KLK1 | P06870 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3834004 | 0.90 | F10 (0.58) | F10F2PLATKLK1 | |
| SCHEMBL1455285 | 0.89 | F10 (0.67) | F10F2KLK1 | |
| SCHEMBL3833120 | 0.88 | F10 (0.64) | F10F2KLK1 | |
| SCHEMBL3838120 | 0.88 | F10 (0.57) | F10F2PLATKLK1 | |
| SCHEMBL1456108 | 0.84 | F10 (0.63) | F10F2 | |
| SCHEMBL3834020 | 0.82 | F10 (0.70) | F10F2KLK1 | |
| SCHEMBL1456127 | 0.81 | F10 (0.68) | F10F2PLATKLK1 | |
| SCHEMBL15911394 | 0.81 | F10 (0.80) | F10F2PLATKLK1 | |
| SCHEMBL4605784 | 0.80 | F10 (0.60) | F10F2PLATKLK1 | |
| SCHEMBL15911592 | 0.79 | F10 (0.66) | F10F2KLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1581523-B1 | PYRAZOLE-DERIVATIVES AS FACTOR XA INHIBITORS | SANOFI AVENTIS DEUTSCHLAND (DE) | 2009-09-30 | — | — | EP | claimed |