⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13516719 | 0.80 | — | — | |
| SCHEMBL8214498 | 0.77 | — | — | |
| SCHEMBL7135442 | 0.75 | HTT (0.31) | — | |
| SCHEMBL16594103 | 0.73 | MEN1 (0.46) | — | |
| SCHEMBL16594107 | 0.73 | MEN1 (0.46) | — | |
| SCHEMBL23829836 | 0.72 | — | — | |
| SCHEMBL11744687 | 0.72 | — | — | |
| SCHEMBL2922779 | 0.72 | MEN1 (0.50) | — | |
| SCHEMBL6890448 | 0.70 | NPSR1 (0.35) | — | |
| SCHEMBL25438034 | 0.70 | CYP1A2 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1650214-B1 | Silicon compound | CHISSO CORP (JP) | 2009-11-04 | — | — | EP | disclosed |
| US-7256243-B2 | Silicon compound | CHISSO CORPORATION (JP) | 2007-08-14 | — | — | US | disclosed |
| EP-1650214-A2 | Silicon compound | CHISSO CORPORATION (JP) | 2006-04-26 | — | — | EP | disclosed |
| US-20050250925-A1 | Silicon compound | JNC CORPORATION (JP) | 2005-11-10 | — | — | US | disclosed |