Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 10/20 | 0.56 |
| ▸ | PPARG | P37231 | 7/20 | 0.56 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 8/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3284656 | 0.94 | PPARA (0.56) | PPARAPPARGPPARDTLR7 | |
| SCHEMBL3291786 | 0.94 | PPARA (0.61) | PPARAPPARGPPARDTLR7 | |
| SCHEMBL3285216 | 0.91 | PPARA (0.60) | PPARAPPARGPPARDTLR7 | |
| SCHEMBL13360138 | 0.91 | PPARA (0.58) | PPARAPPARGPPARDTLR7 | |
| SCHEMBL3285329 | 0.91 | PPARA (0.58) | PPARAPPARGPPARDTLR7 | |
| SCHEMBL3288232 | 0.90 | PPARA (0.59) | PPARAPPARGPPARDTLR7 | |
| SCHEMBL3284207 | 0.89 | PPARA (0.56) | PPARAPPARGPPARDTLR7 | |
| SCHEMBL3286817 | 0.89 | PPARA (0.56) | PPARAPPARGPPARDTLR7 | |
| SCHEMBL3286847 | 0.89 | PPARA (0.56) | PPARAPPARGPPARDTLR7 | |
| SCHEMBL3286648 | 0.89 | PPARA (0.56) | PPARAPPARGPPARDTLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856065-B1 | 1,2,4-TRIAZINE DERIVATIVES, PREPARATION AND USE THEREOF IN HUMAN THERAPY | PF MEDICAMENT (FR) | 2009-11-11 | — | — | EP | claimed |
| EP-1856065-B1 | 1,2,4-TRIAZINE DERIVATIVES, PREPARATION AND USE THEREOF IN HUMAN THERAPY | PF MEDICAMENT (FR) | 2009-11-11 | — | — | EP | disclosed |