Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 19/20 | 0.51 |
| ▸ | PPARG | P37231 | 13/20 | 0.51 |
| ▸ | PPARD | Q03181 | 8/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3841403 | 0.93 | PPARA (0.43) | PPARAPPARGPPARD | |
| SCHEMBL3284481 | 0.92 | PPARA (0.43) | PPARAPPARGPPARD | |
| SCHEMBL3840282 | 0.91 | PPARA (0.49) | PPARAPPARGPPARD | |
| SCHEMBL3844826 | 0.91 | PPARA (0.55) | PPARAPPARGPPARD | |
| SCHEMBL3842008 | 0.88 | PPARA (0.54) | PPARAPPARGPPARD | |
| SCHEMBL3846346 | 0.88 | PPARA (0.54) | PPARAPPARGPPARD | |
| SCHEMBL3840865 | 0.88 | PPARA (0.47) | PPARAPPARGPPARD | |
| SCHEMBL3845479 | 0.88 | PPARA (0.51) | PPARAPPARGPPARD | |
| SCHEMBL3845411 | 0.87 | PPARA (0.51) | PPARAPPARGPPARD | |
| SCHEMBL3845465 | 0.86 | PPARA (0.42) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856065-B1 | 1,2,4-TRIAZINE DERIVATIVES, PREPARATION AND USE THEREOF IN HUMAN THERAPY | PF MEDICAMENT (FR) | 2009-11-11 | — | — | EP | claimed |
| EP-1856065-B1 | 1,2,4-TRIAZINE DERIVATIVES, PREPARATION AND USE THEREOF IN HUMAN THERAPY | PF MEDICAMENT (FR) | 2009-11-11 | — | — | EP | disclosed |
| EP-1856065-A1 | 1,2,4-TRIAZINE DERIVATIVES, PREPARATION AND USE THEREOF IN HUMAN THERAPY | PIERRE FABRE MEDICAMENT (FR) | 2007-11-21 | — | — | EP | disclosed |
| WO-2006092507-A1 | 1,2,4-TRIAZINE DERIVATIVES, PREPARATION AND USE THEREOF IN HUMAN THERAPY | PIERRE FABRE MEDICAMENT (FR) | 2006-09-08 | — | — | WO | disclosed |