Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 9/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3838950 | 0.91 | KCNH2 (0.54) | KCNH2 | |
| SCHEMBL3839529 | 0.89 | KCNH2 (0.44) | KCNH2 | |
| SCHEMBL3843472 | 0.84 | KCNH2 (0.54) | KCNH2 | |
| SCHEMBL3864975 | 0.81 | KCNH2 (0.64) | KCNH2 | |
| SCHEMBL4775985 | 0.81 | KCNH2 (0.58) | KCNH2 | |
| SCHEMBL4136611 | 0.79 | KCNH2 (0.54) | KCNH2 | |
| SCHEMBL4775988 | 0.79 | KCNH2 (0.51) | KCNH2 | |
| SCHEMBL10313896 | 0.79 | KCNH2 (0.49) | KCNH2 | |
| SCHEMBL10313957 | 0.76 | KCNH2 (0.61) | KCNH2 | |
| SCHEMBL12094172 | 0.76 | KCNH2 (0.61) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2044077-A1 | DERIVATIVES AND ANALOGS OF N-ETHYLQUINOLONES AND N-ETHYLAZAQUINOLONES | Glaxo Group Limited (GB) | 2009-04-08 | — | — | EP | disclosed |
| WO-2008009700-A1 | DERIVATIVES AND ANALOGS OF N-ETHYLQUINOLONES AND N-ETHYLAZAQUINOLONES | GLAXO GROUP LIMITED (GB) | 2008-01-24 | — | — | WO | disclosed |