Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.37 |
| ▸ | UTS2R | Q9UKP6 | 2/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 8/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4299494 | 0.81 | TMEM97 (0.48) | TMEM97KCNH2CYP3A4CYP2D6OPRK1 | |
| SCHEMBL3840641 | 0.76 | KCNH2 (0.51) | KCNH2 | |
| SCHEMBL4294752 | 0.75 | KCNH2 (0.57) | TMEM97KCNH2 | |
| Hydrochloric Acid SCHEMBL3858458 | 0.74 | KCNH2 (0.56) | TMEM97KCNH2 | |
| SCHEMBL3840342 | 0.69 | KCNH2 (0.41) | KCNH2 | |
| SCHEMBL2799505 | 0.69 | KCNH2 (0.34) | KCNH2TACR1OPRM1 | |
| SCHEMBL3328622 | 0.69 | TSHR (0.34) | CYP3A4TACR1 | |
| SCHEMBL3149833 | 0.68 | KCNH2 (0.43) | KCNH2 | |
| SCHEMBL3621094 | 0.67 | KCNH2 (0.44) | KCNH2CYP2D6 | |
| SCHEMBL3215289 | 0.67 | KCNH2 (0.38) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2044077-A1 | DERIVATIVES AND ANALOGS OF N-ETHYLQUINOLONES AND N-ETHYLAZAQUINOLONES | Glaxo Group Limited (GB) | 2009-04-08 | — | — | EP | disclosed |
| WO-2008009700-A1 | DERIVATIVES AND ANALOGS OF N-ETHYLQUINOLONES AND N-ETHYLAZAQUINOLONES | GLAXO GROUP LIMITED (GB) | 2008-01-24 | — | — | WO | disclosed |