Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 20/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4468312 | 0.91 | BRAF (0.68) | BRAF | |
| SCHEMBL1792426 | 0.87 | BRAF (0.54) | BRAF | |
| SCHEMBL4457106 | 0.83 | BRAF (0.73) | BRAF | |
| SCHEMBL12652360 | 0.81 | BRAF (0.58) | BRAF | |
| SCHEMBL1793425 | 0.81 | BRAF (0.46) | BRAF | |
| SCHEMBL1795745 | 0.80 | BRAF (0.71) | BRAF | |
| SCHEMBL4464969 | 0.78 | BRAF (0.64) | BRAF | |
| SCHEMBL1794175 | 0.76 | GRM4 (0.43) | — | |
| SCHEMBL1795844 | 0.76 | BRAF (0.61) | BRAF | |
| SCHEMBL4464984 | 0.74 | BRAF (0.67) | BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2013207-A1 | IMIDAZO[4, 5-B]PYRIDIN-2-ONE AND OXAZOLO[4, 5-B]PYRIDIN-2-ONE COMPOUNDS AND ANALOGS THEREOF AS CANCER THERAPEUTIC COMPOUNDS | Cancer Research Technology Limited (GB) | 2009-01-14 | — | — | EP | disclosed |
| WO-2007125330-A1 | IMIDAZO[4, 5-B]PYRIDIN-2-ONE AND OXAZOLO[4, 5-B]PYRIDIN-2-ONE COMPOUNDS AND ANALOGS THEREOF AS CANCER THERAPEUTIC COMPOUNDS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2007-11-08 | — | — | WO | disclosed |