Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CTNNB1 | P35222 | 3/20 | 0.44 |
| ▸ | TCF7L2 | Q9NQB0 | 3/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1736846 | 0.99 | MAPT (0.49) | MAPTKDM4ECTNNB1TCF7L2MAPK10 | |
| Hydrochloric Acid SCHEMBL1738844 | 0.91 | MEN1 (0.43) | MAPTCTNNB1TCF7L2MAPK10KMT2A | |
| SCHEMBL27698535 | 0.91 | CTNNB1 (0.44) | MAPTCTNNB1TCF7L2MAPK10KMT2A | |
| Hydrochloric Acid SCHEMBL1737509 | 0.90 | CTNNB1 (0.44) | MAPTCTNNB1TCF7L2MAPK10KMT2A | |
| Hydrochloric Acid SCHEMBL1737083 | 0.89 | MEN1 (0.51) | MAPTKDM4ECTNNB1TCF7L2MAPK10 | |
| SCHEMBL1738141 | 0.86 | MAPT (0.47) | MAPTKMT2AHTT | |
| Hydrochloric Acid SCHEMBL1736991 | 0.85 | MAPT (0.46) | MAPTKMT2AHTT | |
| SCHEMBL1735914 | 0.84 | MAPT (0.46) | MAPTKMT2AHTT | |
| Hydrochloric Acid SCHEMBL1736968 | 0.84 | MAPT (0.45) | MAPTKMT2AHTT | |
| SCHEMBL5810293 | 0.84 | HSD17B10 (0.44) | MAPTKDM4EKMT2AMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101018789-B | Pyrrolo[2,3-c]pyridine derivatives and processes for the preparation thereof | YUHAN CORP | 2010-09-08 | — | — | CN | claimed |
| EP-1784404-A4 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORP (KR) | 2009-09-09 | — | — | EP | claimed |
| JP-2008511621-A | — | — | 2008-04-17 | — | — | JP | claimed |
| CN-101018789-A | Pyrrolo[2,3-c]pyridine derivatives and processes for the preparation thereof | YUHAN CORP (KR) | 2007-08-15 | — | — | CN | claimed |
| EP-1784404-A1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | Yuhan Corporation (KR) | 2007-05-16 | — | — | EP | claimed |
| WO-2006025716-A1 | PYRROLO[2,3-C]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2006-03-09 | — | — | WO | claimed |