⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13121654 | 0.70 | — | — | |
| SCHEMBL181060 | 0.70 | — | — | |
| SCHEMBL13121750 | 0.70 | — | — | |
| SCHEMBL20494381 | 0.70 | — | — | |
| SCHEMBL21827626 | 0.70 | — | — | |
| SCHEMBL261738 | 0.70 | — | — | |
| SCHEMBL467979 | 0.67 | — | — | |
| SCHEMBL289020 | 0.63 | — | — | |
| SCHEMBL16569728 | 0.60 | — | — | |
| SCHEMBL2458386 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 604 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115010631-A | Compound for removing hydrogen sulfide and mercaptan from natural gas and preparation method thereof | 中国石油化工股份有限公司 | 2022-09-06 | — | — | CN | claimed |
| US-20220055992-A1 | Process for preparing 2-alkoxy-4-amino-5-methyl-pyridines and/or 2-alkoxy-4-alkylamino-5-methyl-pyridines | SALTIGO GMBH (DE) | 2022-02-24 | — | — | US | claimed |
| EP-3898589-A2 | PROCESS FOR PREPARING 2-ALKOXY-4-AMINO-5-METHYL-PYRIDINES AND/OR 2-ALKOXY-4-ALKYLAMINO-5-METHYL-PYRIDINES | Saltigo GmbH (DE) | 2021-10-27 | — | — | EP | claimed |
| CN-113242853-A | Process for the preparation of 2-alkoxy-4-amino-5-methyl-pyridines and/or 2-alkoxy-4-alkylamino-5-methyl-pyridines | 赛拓有限责任公司 | 2021-08-10 | — | — | CN | claimed |
| WO-2020128020-A2 | PROCESS FOR PREPARING 2-ALKOXY-4-AMINO-5-METHYL-PYRIDINES AND/OR 2-ALKOXY-4-ALKYLAMINO-5-METHYL-PYRIDINES | SALTIGO GMBH (DE) | 2020-06-25 | — | — | WO | claimed |
| CN-108779076-A | 5-methyl-6-phenyl-4, 5-dihydro-2H-pyridazin-3-one derivatives | 大塚制药株式会社 | 2018-11-09 | — | — | CN | claimed |
| EP-2970146-B1 | ACYLAMINOCYCLOALKYL COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF DOPAMINE D3 RECEPTOR | ABBVIE DEUTSCHLAND (DE) | 2017-11-01 | — | — | EP | claimed |
| CN-106187838-A | Arylalkyne hydrocarbon compound and its production and use | 广东东阳光药业有限公司 | 2016-12-07 | — | — | CN | claimed |
| US-9481676-B2 | Azepino[4,5-B]indoles and methods of use | MEDIVATION TECHNOLOGIES, INC. (US) | 2016-11-01 | — | — | US | claimed |
| CN-104447450-B | Cysteine amide-type pleuromutilin derivative and preparation method and medical usage | 南通大学 | 2016-09-28 | — | — | CN | claimed |
| WO-2010051503-A1 | AZEPINO [4, 5-B] INDOLES AND METHODS OF USE | MEDIVATION TECHNOLOGIES, INC. (US) | 2010-05-06 | — | — | WO | claimed |
| US-20100105744-A1 | SUBSTITUTED 7-SULFANYLMETHYL-, 7-SULFINYLMETHYL- AND 7-SULFONYLMETHYLINDOLES AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2010-04-29 | — | — | US | claimed |
| WO-2009156072-A1 | SUBSTITUTED 7-SULFANYLMETHYL, 7-SULFINYLMETHYL AND 7-SULFONYLMETHYL INDOLES AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-12-30 | — | — | WO | claimed |
| WO-2006074919-A2 | 3-AMINO-6-ARYL(OR 6-HETEROARYL)-THIENO[2,3-B]PYRIDIN-2-CARBOXAMIDES, PHARMACEUTICAL PREPARATIONS CONTAINING THE SAME AND THEIR USE AS TNFα INHIBITORS | CURACYTE DISCOVERY GMBH (DE) | 2006-07-20 | — | — | WO | claimed |
| EP-1681292-A1 | 3-Amino-6-aryl(or 6-heteroaryl)-thieno¬2,3-b|pyridin-2-carboxylic acid amides, pharmaceutical compositions comprising the said and their use as inhibitors of TNFalpha release | IBFB Pharma GmbH (DE) | 2006-07-19 | — | — | EP | claimed |
| CN-1059336-A | Anti-fungal triazole derivatives and preparation thereof and purposes | SANKYO CO (JP) | 1992-03-11 | — | — | CN | claimed |
| EP-0473387-A2 | Anti-fungal triazole derivatives, their preparation and uses | Sankyo Company Limited (JP) | 1992-03-04 | — | — | EP | claimed |
| EP-0178743-B1 | NOVEL TRITIUM LABELLED N-MUSTARD TYPE COMPOUNDS AND A PROCESS FOR THEIR PRODUCTION | UNIVERSITY OF PITTSBURGH (US) | 1990-05-23 | — | — | EP | claimed |
| US-4795627-A | AZIRIDINIUM ANALOG USED TO EVALUATE THE MECHANISM OF NEUROTRANSMITTER REGULATION | UNIVERSITY OF PITTSBURGH (US) | 1989-01-03 | — | — | US | claimed |
| EP-0178743-A2 | Novel tritium labelled N-mustard type compounds and a process for their production | UNIVERSITY OF PITTSBURGH (US) | 1986-04-23 | — | — | EP | claimed |