Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3161028 | 0.81 | KDM4E (0.41) | KDM4EALDH1A1TSHRPOLB | |
| SCHEMBL3176785 | 0.76 | — | — | |
| SCHEMBL16774583 | 0.71 | KDM4E (0.40) | KDM4EALDH1A1TSHR | |
| SCHEMBL11354719 | 0.71 | KDM4E (0.42) | KDM4EALDH1A1TSHR | |
| SCHEMBL28517018 | 0.68 | KDM4E (0.39) | KDM4EALDH1A1TSHR | |
| SCHEMBL19318513 | 0.68 | POLB (0.59) | ALDH1A1TSHRPOLB | |
| SCHEMBL28358210 | 0.68 | KDM4E (0.40) | KDM4EALDH1A1TSHR | |
| SCHEMBL16287666 | 0.68 | KDM4E (0.40) | KDM4EALDH1A1TSHR | |
| SCHEMBL7281160 | 0.67 | KDM4E (0.33) | KDM4EALDH1A1 | |
| SCHEMBL16178136 | 0.67 | KDM4E (0.47) | KDM4EALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099754-A1 | ION CHANNEL MODULATORS | Wyeth a Corporation of the State of Delaware (US) | 2009-09-16 | — | — | EP | disclosed |
| WO-2008073929-A1 | ION CHANNEL MODULATORS | WYETH (US) | 2008-06-19 | — | — | WO | disclosed |