Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3570546 | 0.89 | HDAC2 (0.53) | HDAC1HDAC2 | |
| SCHEMBL3563743 | 0.83 | HDAC2 (0.54) | HDAC1HDAC2 | |
| SCHEMBL3568753 | 0.80 | HDAC2 (0.53) | HDAC1HDAC2 | |
| SCHEMBL3565002 | 0.80 | HDAC2 (0.53) | HDAC1HDAC2 | |
| SCHEMBL3565882 | 0.80 | HDAC2 (0.53) | HDAC1HDAC2 | |
| SCHEMBL3573817 | 0.79 | HDAC2 (0.52) | HDAC1HDAC2 | |
| SCHEMBL3570977 | 0.77 | HDAC2 (0.54) | HDAC1HDAC2 | |
| SCHEMBL3569985 | 0.76 | HDAC2 (0.49) | HDAC1HDAC2 | |
| SCHEMBL3577453 | 0.75 | HDAC2 (0.47) | HDAC1HDAC2 | |
| SCHEMBL3565273 | 0.74 | HDAC1 (0.51) | HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1874295-A4 | BENZOTHIOPHENE DERIVATIVES | MERCK & CO INC (US) | 2009-08-12 | — | — | EP | disclosed |
| EP-1874295-A1 | BENZOTHIOPHENE DERIVATIVES | Merck & Co., Inc. (US) | 2008-01-09 | — | — | EP | disclosed |
| WO-2006115845-A1 | BENZOTHIOPHENE DERIVATIVES | MERCK & CO., INC. (US) | 2006-11-02 | — | — | WO | disclosed |