Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 20/20 | 0.80 |
| ▸ | ITGB2 | P05107 | 10/20 | 0.80 |
| ▸ | ICAM1 | P05362 | 10/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3843038 | 1.00 | ITGAL (0.80) | ITGALITGB2ICAM1 | |
| SCHEMBL3843166 | 0.89 | ITGAL (1.00) | ITGALITGB2ICAM1 | |
| SCHEMBL3843167 | 0.89 | ITGAL (1.00) | ITGALITGB2ICAM1 | |
| SCHEMBL14045863 | 0.86 | ITGAL (0.83) | ITGALITGB2ICAM1 | |
| SCHEMBL14571206 | 0.86 | ITGAL (0.83) | ITGALITGB2ICAM1 | |
| SCHEMBL3840797 | 0.84 | ITGAL (0.82) | ITGALITGB2ICAM1 | |
| SCHEMBL3840795 | 0.84 | ITGAL (0.82) | ITGALITGB2ICAM1 | |
| SCHEMBL5839417 | 0.83 | ITGAL (0.77) | ITGALITGB2ICAM1 | |
| SCHEMBL5839416 | 0.83 | ITGAL (0.77) | ITGALITGB2ICAM1 | |
| SCHEMBL14560612 | 0.83 | ITGAL (0.77) | ITGALITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1432700-B1 | SPIRO-HYDANTOIN COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | BRISTOL MYERS SQUIBB CO (US) | 2009-11-04 | — | — | EP | disclosed |
| US-7078420-B2 | Spiro-hydantoin compounds useful as anti-inflammatory agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-07-18 | — | — | US | disclosed |
| US-6977267-B2 | Spiro-hydantoin compounds useful as anti-inflammatory agents | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-12-20 | — | — | US | disclosed |