⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodomethane SCHEMBL13098007 | 1.00 | — | — | |
| Iodomethane SCHEMBL11184727 | 1.00 | — | — | |
| Iodomethane SCHEMBL498 | 1.00 | — | — | |
| Iodomethane SCHEMBL2757578 | 1.00 | — | — | |
| Iodomethane SCHEMBL12143615 | 1.00 | — | — | |
| Iodomethane SCHEMBL1626610 | 0.87 | — | — | |
| Iodomethane SCHEMBL5037543 | 0.87 | — | — | |
| Iodomethane SCHEMBL6384004 | 0.87 | — | — | |
| Iodomethane SCHEMBL2432501 | 0.87 | — | — | |
| Iodomethane SCHEMBL22041577 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 80 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003070243-A1 | DI-ESTER DERIVATIVES AS SHORT ACTING NEUROMUSCULAR BLOCKERS | THERASCI LIMITED (GB) | 2003-08-28 | — | — | WO | claimed |
| WO-1998025885-A1 | ANTHRAQUINONES WITH BIOLOGICAL ACTIVITY | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1998-06-18 | — | — | WO | claimed |
| WO-1998025884-A1 | FURTHER ANTHRAQUINONES WITH BIOLOGICAL ACTIVITY | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 1998-06-18 | — | — | WO | claimed |
| US-20230390232-A1 | N-PROPARGYLGLYCINE: A UNIQUE INHIBITOR OF PROLINE DEHYDROGENASE WITH BRAIN-ENHANCING MITOHORMESIS PROPERTIES CAPABLE OF MITIGATING THE PATHOGENESIS OF NEURODEGENERATIVE DISORDERS | NATIONAL INSTITUTES OF HEALTH | 2023-12-07 | — | — | US | disclosed |
| US-20220390454-A1 | BIOMARKER PANEL TARGETED TO DISEASES DUE TO MULTIFACTORIAL ONTOLOGY OF GLYCOCALYX DISRUPTION | ARTEREZ, INC. (US) | 2022-12-08 | — | — | US | disclosed |
| WO-2022094565-A1 | N-PROPARGYLGLYCINE: A UNIQUE INHIBITOR OF PROLINE DEHYDROGENASE WITH BRAIN-ENHANCING MITOHORMESIS PROPERTIES CAPABLE OF MITIGATING NEURODEGENERATIVE DISORDERS | BUCK INSTITUTE FOR RESEARCH ON AGING (US) | 2022-05-05 | — | — | WO | disclosed |
| WO-2021062298-A1 | BIOMARKER PANEL TARGETED TO DISEASES DUE TO MULTIFACTORIAL ONTOLOGY OF GLYCOCALYX DISRUPTION | ARTEREZ, INC. (US) | 2021-04-01 | — | — | WO | disclosed |
| WO-2020008503-A1 | METHOD FOR PRODUCING ACETIC ACID | 株式会社ダイセル | 2020-01-09 | — | — | WO | disclosed |
| CN-107428655-B | Acetic acid process | 利安德巴塞尔乙酰有限责任公司 | 2019-06-04 | — | — | CN | disclosed |
| CN-109776553-A | Own element of good fortune and its preparation method and application | 山东师范大学 | 2019-05-21 | — | — | CN | disclosed |
| CN-109678872-A | Bisbenzylisoquinolincompounds compounds and its preparation method and application | 山东师范大学 | 2019-04-26 | — | — | CN | disclosed |
| US-4414220-A | HUPOGLYCEMIC, ANTIDIABETIC | PFIZER INC. (US) | 1983-11-08 | — | — | US | disclosed |
| US-4333932-A | DIHYDROISOINDOLES, HYPOGLYCEMIC, ANTIDIABETIC | PFIZER INC. (US) | 1982-06-08 | — | — | US | disclosed |
| EP-0010896-B1 | ORGANIC DIAMINE COMPOUNDS FOR USE AS ORAL HYPOGLYCEMIC AGENTS AND PHARMACEUTICAL COMPOSITIONS THEREOF | PFIZER INC. (US) | 1981-12-30 | — | — | EP | disclosed |
| US-4291030-A | Method of lowering blood cholesterol | UNIMED, INC. (US) | 1981-09-22 | — | — | US | disclosed |
| US-4220650-A | HYPOGLYCEMIC | PFIZER INC. (US) | 1980-09-02 | — | — | US | disclosed |
| EP-0010896-A1 | Organic diamine compounds for use as oral hypoglycemic agents and pharmaceutical compositions thereof | PFIZER INC. (US) | 1980-05-14 | — | — | EP | disclosed |
| US-4048322-A | Bronchially effective xanthene-9-carboxylates | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1977-09-13 | — | — | US | disclosed |
| US-4044146-A | CHOLINOLYTIC, BRONCHOSPASMOLYTIC | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1977-08-23 | — | — | US | disclosed |
| US-3998820-A | 4-DIAZABICYCLO-4,M,O-ALKANYL-ACYL)-PHENOTHIAZINES, THEIR ACIDIC ADDITION SALTS AND QUATERNARY SALTS, PROCESS FOR PRODUCING SAME AND USESPASMOLYTICS; CORONARY DILATANTS | LIKHOSHERSTOV ARKADY MIKHAILOV | 1976-12-21 | — | — | US | disclosed |