Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 12/20 | 0.43 |
| ▸ | PPARG | P37231 | 8/20 | 0.43 |
| ▸ | PPARD | Q03181 | 5/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3847350 | 0.88 | PPARA (0.39) | PPARAPPARGPPARDABCB11CYP1A2 | |
| SCHEMBL3845612 | 0.83 | PPARA (0.42) | PPARAPPARGPPARDABCB11CYP1A2 | |
| SCHEMBL3288281 | 0.81 | PPARA (0.46) | PPARAPPARGPPARDTLR7ABCB11 | |
| SCHEMBL3285481 | 0.81 | PPARA (0.45) | PPARAPPARGPPARDABCB11CYP1A2 | |
| SCHEMBL3284508 | 0.79 | PPARA (0.47) | PPARAPPARGPPARDTLR7 | |
| SCHEMBL3291814 | 0.77 | PPARA (0.46) | PPARAPPARGPPARDABCB11CYP1A2 | |
| SCHEMBL3285953 | 0.76 | PPARA (0.48) | PPARAPPARGPPARD | |
| SCHEMBL3285097 | 0.76 | PPARA (0.46) | PPARAPPARGPPARDABCB11CYP1A2 | |
| SCHEMBL3841065 | 0.75 | PPARA (0.45) | PPARAPPARGPPARDADRB3 | |
| SCHEMBL6510038 | 0.75 | PPARA (0.51) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856065-B1 | 1,2,4-TRIAZINE DERIVATIVES, PREPARATION AND USE THEREOF IN HUMAN THERAPY | PF MEDICAMENT (FR) | 2009-11-11 | — | — | EP | claimed |