Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3843523 | 1.00 | CNR1 (0.47) | CNR1CNR2HDAC8KDM4EALDH1A1 | |
| SCHEMBL2767996 | 0.99 | CNR1 (0.48) | CNR1CNR2HDAC8KDM4EALDH1A1 | |
| SCHEMBL2767992 | 0.99 | CNR1 (0.48) | CNR1CNR2HDAC8KDM4EALDH1A1 | |
| SCHEMBL3212785 | 0.85 | CNR1 (0.43) | CNR1CNR2HDAC8KDM4EALDH1A1 | |
| SCHEMBL3212794 | 0.85 | CNR1 (0.43) | CNR1CNR2HDAC8KDM4EALDH1A1 | |
| SCHEMBL2772203 | 0.80 | HDAC8 (0.43) | CNR1CNR2HDAC8KDM4EALDH1A1 | |
| SCHEMBL2772199 | 0.80 | HDAC8 (0.43) | CNR1CNR2HDAC8KDM4EALDH1A1 | |
| SCHEMBL3212801 | 0.79 | PSEN1 (0.48) | CNR1CNR2 | |
| SCHEMBL2767358 | 0.77 | CNR2 (0.56) | CNR1CNR2KDM4EALDH1A1LMNA | |
| SCHEMBL3212790 | 0.76 | CNR1 (0.44) | CNR1CNR2KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2044077-A1 | DERIVATIVES AND ANALOGS OF N-ETHYLQUINOLONES AND N-ETHYLAZAQUINOLONES | Glaxo Group Limited (GB) | 2009-04-08 | — | — | EP | disclosed |
| WO-2008009700-A1 | DERIVATIVES AND ANALOGS OF N-ETHYLQUINOLONES AND N-ETHYLAZAQUINOLONES | GLAXO GROUP LIMITED (GB) | 2008-01-24 | — | — | WO | disclosed |