Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP7 | Q9UHL4 | 6/20 | 0.61 |
| ▸ | DPP4 | P27487 | 6/20 | 0.61 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.61 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.61 |
| ▸ | FAP | Q12884 | 2/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | AKT1 | P31749 | 1/20 | 0.45 |
| ▸ | AKT2 | P31751 | 1/20 | 0.45 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | PRCP | P42785 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8385358 | 0.90 | DPP7 (0.72) | DPP7DPP4DPP8DPP9FAP | |
| SCHEMBL19923028 | 0.88 | DPP7 (0.61) | DPP7DPP4DPP8DPP9FAP | |
| SCHEMBL19923030 | 0.88 | DPP7 (0.61) | DPP7DPP4DPP8DPP9FAP | |
| SCHEMBL18049261 | 0.84 | DPP7 (0.57) | DPP7DPP4DPP8DPP9FAP | |
| SCHEMBL18049265 | 0.84 | DPP7 (0.57) | DPP7DPP4DPP8DPP9FAP | |
| SCHEMBL13727820 | 0.83 | DPP7 (0.56) | DPP7DPP4DPP8DPP9FAP | |
| SCHEMBL13456371 | 0.83 | DPP7 (0.56) | DPP7DPP4DPP8DPP9FAP | |
| SCHEMBL12618900 | 0.83 | DPP7 (0.56) | DPP7DPP4DPP8DPP9FAP | |
| SCHEMBL6162970 | 0.82 | DPP4 (0.73) | DPP7DPP4DPP8DPP9FAP | |
| SCHEMBL19922947 | 0.82 | DPP7 (0.60) | DPP7DPP4DPP8DPP9FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1799665-B1 | METHOD FOR CLEANING 3-HYDROXYAMIDINOPHENYLALANINE DERIVATIVES BY THE PRECIPITATION AND RECRYSTALLISATION OF A SALT AND AN AROMATIC SULPHONIC ACID | WILEX AG (DE) | 2009-08-19 | — | — | EP | claimed |
| WO-2016144654-A1 | INHIBITORS OF GROWTH FACTOR ACTIVATION ENZYMES | WASHINGTON UNIVERSITY (US) | 2016-09-15 | — | — | WO | disclosed |
| CN-101039928-B | Method for purifying 3-hydroxyamidinophenylalanine derivatives by precipitation and recrystallization using salts of aromatic sulfonic acids | WILEX AG | 2010-12-08 | — | — | CN | disclosed |
| EP-1799665-B1 | METHOD FOR CLEANING 3-HYDROXYAMIDINOPHENYLALANINE DERIVATIVES BY THE PRECIPITATION AND RECRYSTALLISATION OF A SALT AND AN AROMATIC SULPHONIC ACID | WILEX AG (DE) | 2009-08-19 | — | — | EP | disclosed |
| CN-101039928-A | Method for purifying 3-hydroxyamidinophenylalanine derivatives by precipitation and recrystallization using salts of aromatic sulfonic acids | WILEX AG (DE) | 2007-09-19 | — | — | CN | disclosed |
| EP-1799665-A1 | METHOD FOR CLEANING 3-HYDROXYAMIDINOPHENYLALANINE DERIVATIVES BY THE PRECIPITATION AND RECRYSTALLISATION OF A SALT AND AN AROMATIC SULPHONIC ACID | Wilex AG (DE) | 2007-06-27 | — | — | EP | disclosed |
| WO-2006042678-A1 | METHOD FOR CLEANING 3-HYDROXYAMIDINOPHENYLALANINE DERIVATIVES BY THE PRECIPITATION AND RECRYSTALLISATION OF A SALT AND AN AROMATIC SULPHONIC ACID | WILEX AG (DE) | 2006-04-27 | — | — | WO | disclosed |
| EP-1525195-A2 | METHOD FOR THE PRODUCTION OF PHENYLALANINE DERIVATIVES | Wilex AG (DE) | 2005-04-27 | — | — | EP | disclosed |
| WO-2004011449-A2 | METHOD FOR THE PRODUCTION OF PHENYLALANINE DERIVATIVES | WILEX AG (DE) | 2004-02-05 | — | — | WO | disclosed |