Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 9/20 | 0.48 |
| ▸ | PPARG | P37231 | 6/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3841989 | 0.96 | PPARA (0.46) | PPARAPPARGPPARDADORA3CYP2D6 | |
| SCHEMBL3841464 | 0.94 | PPARA (0.48) | PPARAPPARGPPARDADORA3MTNR1A | |
| SCHEMBL3841118 | 0.92 | PPARA (0.40) | PPARAPPARGPPARDMTNR1AMTNR1B | |
| SCHEMBL3844887 | 0.92 | PPARA (0.52) | PPARAPPARGPPARDADORA3LMNA | |
| SCHEMBL3844352 | 0.91 | PPARA (0.48) | PPARAPPARGPPARDADORA3CYP2D6 | |
| SCHEMBL3849183 | 0.91 | PPARA (0.60) | PPARAPPARGPPARDADORA3MTNR1A | |
| SCHEMBL3844889 | 0.90 | PPARA (0.42) | PPARAPPARGPPARDCYP2D6 | |
| SCHEMBL3849215 | 0.90 | PPARA (0.45) | PPARAPPARGPPARDADORA3TLR7 | |
| SCHEMBL3844298 | 0.89 | PPARA (0.51) | PPARAPPARGPPARDADORA3LMNA | |
| SCHEMBL3840689 | 0.89 | PPARA (0.47) | PPARAPPARGPPARDADORA3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1856065-B1 | 1,2,4-TRIAZINE DERIVATIVES, PREPARATION AND USE THEREOF IN HUMAN THERAPY | PF MEDICAMENT (FR) | 2009-11-11 | — | — | EP | claimed |