SCHEMBL3844599

SCHEMBL3844599

CC(C)(Oc1ccc(O)cc1)C(=O)O

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 10/20 0.69
MEN1 O00255 3/20 0.69
KMT2A Q03164 3/20 0.69
CYP2C19 P33261 2/20 0.69
CYP1A2 P05177 1/20 0.69
CYP3A4 P08684 1/20 0.69
CYP2D6 P10635 1/20 0.69
MAPT P10636 1/20 0.69
PPARG P37231 10/20 0.65
FABP2 P12104 1/20 0.59
SLC22A12 Q96S37 1/20 0.59
TSHR P16473 2/20 0.54
LMNA P02545 2/20 0.54
KDM4E B2RXH2 2/20 0.54
CYP2C9 P11712 2/20 0.54
ALDH1A1 P00352 1/20 0.54
POLB P06746 1/20 0.54
BLM P54132 1/20 0.54
PPARD Q03181 3/20 0.51
TBXAS1 P24557 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fenofibrate Acid SCHEMBL22373737 0.91 PPARG (0.73) PPARAMEN1KMT2ACYP2C19CYP1A2
SCHEMBL11545612 0.85 PPARA (0.71) PPARAMEN1KMT2ACYP2C19CYP1A2
SCHEMBL1045831 0.83 PPARA (0.69) PPARAMEN1KMT2ACYP2C19CYP1A2
SCHEMBL4653170 0.83 PPARA (0.69) PPARAMEN1KMT2ACYP2C19CYP1A2
SCHEMBL247466 0.83 PPARA (0.68) PPARAMEN1KMT2ACYP2C19CYP1A2
SCHEMBL9735030 0.82 PPARA (0.67) PPARAMEN1KMT2ACYP2C19CYP1A2
SCHEMBL11756293 0.82 PPARA (0.67) PPARAMEN1KMT2ACYP2C19CYP1A2
SCHEMBL787522 0.82 PPARA (0.67) PPARAMEN1KMT2ACYP2C19CYP1A2
Clofibric Acid SCHEMBL102826 0.82 PPARA (1.00) PPARAMEN1KMT2ACYP2C19CYP1A2
SCHEMBL2131476 0.82 PPARA (0.67) PPARAMEN1KMT2ACYP2C19CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119562975-A Composition containing ester compound and method for producing same, polymerizable composition, (meth) acrylic polymer, and method for producing same 三菱化学株式会社 2025-03-04 CN disclosed
EP-2310371-B1 PPAR AGONIST COMPOUNDS AND PREPARATION AND USES THEREOF FOR TREATING DIABETES AND/OR DYSLIPIDEMIA GENFIT (FR) 2013-05-15 EP disclosed
EP-1856065-B1 1,2,4-TRIAZINE DERIVATIVES, PREPARATION AND USE THEREOF IN HUMAN THERAPY PF MEDICAMENT (FR) 2009-11-11 EP disclosed
EP-1856065-A1 1,2,4-TRIAZINE DERIVATIVES, PREPARATION AND USE THEREOF IN HUMAN THERAPY PIERRE FABRE MEDICAMENT (FR) 2007-11-21 EP disclosed
WO-2006092507-A1 1,2,4-TRIAZINE DERIVATIVES, PREPARATION AND USE THEREOF IN HUMAN THERAPY PIERRE FABRE MEDICAMENT (FR) 2006-09-08 WO disclosed
WO-2006035157-A2 SUBSTITUTED N-(BENZYL)PHENYLACETAMIDE DERIVATIVE COMPOUNDS, PREPARATION METHOD THEREOF AND USES OF SAME AS PPAR LIGANDS IN THE TREATMENT OF LIPID AND/OR GLUCIDIC DISORDERS GENFIT (FR) 2006-04-06 WO disclosed
EP-0621255-B1 Substituted phenoxy-isobutyric acids and esters ADIR (FR) 1997-08-20 EP disclosed
EP-0621255-A1 Substituted phenoxy-isobutyric acids and esters ADIR ET COMPAGNIE (FR) 1994-10-26 EP disclosed
US-5108916-A Racemic mixtures RHONE-POULENC RORER, S.A. (FR) 1992-04-28 US disclosed
EP-0407033-A2 Lipase and isozymes, notably of Candida rugosa, and their use RHONE-POULENC INC. (US) 1991-01-09 EP disclosed
EP-0129851-B1 PREPARATION OF MONOALKYLATED DIHYDROXYBENZENES AND NOVEL COMPOUNDS PREPARED THEREBY THE DOW CHEMICAL COMPANY (US) 1988-07-13 EP disclosed
US-4691042-A Preparation of monaoalkylated dihydroxybenzenes and novel compounds prepared thereby THE DOW CHEMICAL COMPANY (US) 1987-09-01 US disclosed
US-4568497-A Preparation of monoalkylated dihydroxybenzenes THE DOW CHEMICAL COMPANY (US) 1986-02-04 US disclosed
US-4561882-A HERBICIDES ZOECON CORPORATION (US) 1985-12-31 US disclosed
US-4511731-A 2-Ethoxyethyl 2-(4-hydroxyphenoxy)-propanoate THE DOW CHEMICAL COMPANY (US) 1985-04-16 US disclosed
EP-0129851-A2 Preparation of monoalkylated dihydroxybenzenes and novel compounds prepared thereby THE DOW CHEMICAL COMPANY (US) 1985-01-02 EP disclosed
US-4205978-A Novel herbicidally active, nuclear-substituted phenoxy-phenoxyalkanecarboxylic acid derivatives and use thereof for controlling grass-like weeds ISHIHARA SANGYO KAISHA, LTD. (JP) 1980-06-03 US disclosed
US-4193790-A Novel herbicidally active, nuclear-substituted phenoxy-phenoxy-alkanecarboxylic acid derivatives and use thereof for controlling grass-like weeds Ishihara Sangyo Kabushiki Kaisha Ltd. (JP) 1980-03-18 US disclosed
US-4183743-A IN CROPS OF PLANTS SUCH AS CEREALS ISHIHARA SANGYO KAISHA LTD. (JP) 1980-01-15 US disclosed
US-4106925-A PREEMERGENT AND POSTEMERGENT ISHIHARA SANGYO KAISHA LTD. (JP) 1978-08-15 US disclosed