Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 13/20 | 0.46 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4296898 | 0.83 | KCNH2 (0.49) | KCNH2 | |
| SCHEMBL3841807 | 0.78 | KCNH2 (0.53) | KCNH2 | |
| SCHEMBL4297799 | 0.77 | KCNH2 (0.58) | KCNH2 | |
| Hydrochloric Acid SCHEMBL4300805 | 0.76 | KCNH2 (0.57) | KCNH2 | |
| SCHEMBL4301272 | 0.76 | KCNH2 (0.53) | KCNH2 | |
| SCHEMBL4777362 | 0.76 | KCNH2 (0.47) | KCNH2 | |
| SCHEMBL3841802 | 0.73 | KCNH2 (0.54) | KCNH2 | |
| SCHEMBL12047117 | 0.72 | KCNH2 (0.68) | KCNH2 | |
| SCHEMBL4305567 | 0.72 | KCNH2 (0.64) | KCNH2 | |
| SCHEMBL2799173 | 0.71 | KCNH2 (0.56) | KCNH2KCNQ1CACNA1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2044077-A1 | DERIVATIVES AND ANALOGS OF N-ETHYLQUINOLONES AND N-ETHYLAZAQUINOLONES | Glaxo Group Limited (GB) | 2009-04-08 | — | — | EP | disclosed |
| WO-2008009700-A1 | DERIVATIVES AND ANALOGS OF N-ETHYLQUINOLONES AND N-ETHYLAZAQUINOLONES | GLAXO GROUP LIMITED (GB) | 2008-01-24 | — | — | WO | disclosed |