Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.89 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | TAS1R3 | Q7RTX0 | 4/20 | 0.53 |
| ▸ | TAS1R1 | Q7RTX1 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | F3 | P13726 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Octinoxate SCHEMBL30252195 | 0.94 | TDP1 (1.00) | TDP1LMNATAS1R3TAS1R1SMN1; SMN2 | |
| Octinoxate SCHEMBL12533330 | 0.94 | TDP1 (1.00) | TDP1LMNATAS1R3TAS1R1SMN1; SMN2 | |
| Octinoxate SCHEMBL15609 | 0.94 | TDP1 (1.00) | TDP1LMNATAS1R3TAS1R1SMN1; SMN2 | |
| Octinoxate SCHEMBL15803545 | 0.94 | TDP1 (1.00) | TDP1LMNATAS1R3TAS1R1SMN1; SMN2 | |
| Octinoxate SCHEMBL39360 | 0.94 | TDP1 (1.00) | TDP1LMNATAS1R3TAS1R1SMN1; SMN2 | |
| Octinoxate SCHEMBL1768913 | 0.94 | TDP1 (1.00) | TDP1LMNATAS1R3TAS1R1SMN1; SMN2 | |
| Octinoxate SCHEMBL28243144 | 0.93 | TDP1 (0.98) | TDP1LMNATAS1R3TAS1R1SMN1; SMN2 | |
| Octinoxate SCHEMBL20590507 | 0.90 | TDP1 (0.87) | TDP1LMNATAS1R3TAS1R1SMN1; SMN2 | |
| SCHEMBL9098850 | 0.90 | TDP1 (0.91) | TDP1LMNATAS1R3TAS1R1SMN1; SMN2 | |
| SCHEMBL1960360 | 0.90 | TDP1 (0.91) | TDP1LMNATAS1R3TAS1R1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1420645-B1 | MULTIVESICULAR EMULSION TOPICAL DELIVERY SYSTEMS | HEALTHPOINT LTD (US) | 2009-11-04 | — | — | EP | disclosed |